AUTHOR=Zhu Liwei , Liu Yuzhe , Wang Ao , Zhu Zhengqing , Li Youbin , Zhu Chenyi , Che Zhenjia , Liu Tengyue , Liu He , Huang Lanfeng TITLE=Application of BMP in Bone Tissue Engineering JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2022.810880 DOI=10.3389/fbioe.2022.810880 ISSN=2296-4185 ABSTRACT=
At present, bone nonunion and delayed union are still difficult problems in orthopaedics. Since the discovery of bone morphogenetic protein (BMP), it has been widely used in various studies due to its powerful role in promoting osteogenesis and chondrogenesis. Current results show that BMPs can promote healing of bone defects and reduce the occurrence of complications. However, the mechanism of BMP