AUTHOR=Cheng Yue , Bailly Rodolphe , Scavinner-Dorval Claire , Fouquet Benjamin , Borotikar Bhushan , Ben Salem Douraied , Brochard Sylvain , Rousseau François TITLE=Comprehensive personalized ankle joint shape analysis of children with cerebral palsy from pediatric MRI JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2022.1059129 DOI=10.3389/fbioe.2022.1059129 ISSN=2296-4185 ABSTRACT=

Cerebral palsy, a common physical disability in childhood, often causes abnormal patterns of movement and posture. To better understand the pathology and improve rehabilitation of patients, a comprehensive bone shape analysis approach is proposed in this article. First, a group analysis is performed on a clinical MRI dataset using two state-of-the-art shape analysis methods: ShapeWorks and a voxel-based method relying on Advanced Normalization Tools (ANTs) registration. Second, an analysis of three bones of the ankle is done to provide a complete view of the ankle joint. Third, a bone shape analysis is carried out at subject level to highlight variability patterns for personnalized understanding of deformities.