AUTHOR=Xiao Xiao , Teng Fei , Shi Changkuo , Chen Junyu , Wu Shuqing , Wang Bao , Meng Xiang , Essiet Imeh Aniekan , Li Wenliang 

TITLE=Polymeric nanoparticles—Promising carriers for cancer therapy

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2022.1024143

DOI=10.3389/fbioe.2022.1024143

ISSN=2296-4185

ABSTRACT=<p>Polymeric nanoparticles (NPs) play an important role in controlled cancer drug delivery. Anticancer drugs can be conjugated or encapsulated by polymeric nanocarriers, which are known as polymeric nanomedicine. Polymeric nanomedicine has shown its potential in providing sustained release of drugs with reduced cytotoxicity and modified tumor retention, but until now, few delivery systems loading drugs have been able to meet clinical demands, so more efforts are needed. This research reviews the current state of the cancer drug-loading system by exhibiting a series of published articles that highlight the novelty and functions from a variety of different architectures including micelles, liposomes, dendrimers, polymersomes, hydrogels, and metal–organic frameworks. These may contribute to the development of useful polymeric NPs to achieve different therapeutic purposes.</p>