AUTHOR=Chen Yiwen , Zhu Huilin , Hao Yuanping , Sun Zhanyi , Shen Peili , Zhou Qihui TITLE=Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2021.739209 DOI=10.3389/fbioe.2021.739209 ISSN=2296-4185 ABSTRACT=
Sulfated polysaccharide fucoidan (FD) is widely applied in biomedical applications owing to its outstanding bioactivities. In addition to the biochemical features, the architecture of biomaterials plays a critical role in tissue repair and regeneration. Particularly, nanofibers have elicited great interest due to their extracellular matrix-like structure, high specific surface area, and favorable biological properties. Herein, chitosan-modified FD/ultra-high molecular weight polyethylene oxide (UHMWPEO) nanofibers are developed