AUTHOR=Narayanan Theyencheri , Rüter Axel , Olsson Ulf TITLE=SAXS/WAXS Investigation of Amyloid-β(16-22) Peptide Nanotubes JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2021.654349 DOI=10.3389/fbioe.2021.654349 ISSN=2296-4185 ABSTRACT=

This brief report presents an X-ray scattering investigation of self-assembled nanotubes formed by a short peptide. X-ray scattering methods enable multiscale structural elucidation of these nanotubes in solution under the same conditions involved in the self-assembly process. In particular, the dimensions of nanotubes and the crystalline organization within their walls can be determined quantitatively. This is illustrated in the case of amyloid-β(16-22) peptide nanotubes.