AUTHOR=Greene James M. , Sanchez-Tapia Cynthia , Sontag Eduardo D. TITLE=Mathematical Details on a Cancer Resistance Model JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=8 YEAR=2020 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2020.00501 DOI=10.3389/fbioe.2020.00501 ISSN=2296-4185 ABSTRACT=
One of the most important factors limiting the success of chemotherapy in cancer treatment is the phenomenon of drug resistance. We have recently introduced a framework for quantifying the effects of induced and non-induced resistance to cancer chemotherapy (Greene et al.,