AUTHOR=Vlamidis Ylea , Voliani Valerio 

TITLE=Bringing Again Noble Metal Nanoparticles to the Forefront of Cancer Therapy

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=6

YEAR=2018

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2018.00143

DOI=10.3389/fbioe.2018.00143

ISSN=2296-4185

ABSTRACT=<p>Nanomaterials have attracted increasing interest for their potentiality to revolutionize the diagnosis and treatment of many diseases, especially neoplasms. Interestingly, there is a huge imbalance between the number of proposed nanoplatforms and the few ones approved for clinical applications. This disequilibrium affects in particular noble metal nanoparticles (NPs), that present no-approved platform and very few candidates in clinical trials because of the issue of persistence. In this perspective, we discuss if nanomedicine is generally keeping its promises with a focus on the approach that could fill the gap between NPs and oncology in the next future: the ultrasmall-in-nano.</p>