AUTHOR=Picó-Pérez Maria , Magalhães Ricardo , Esteves Madalena , Vieira Rita , Castanho Teresa C. , Amorim Liliana , Sousa Mafalda , Coelho Ana , Moreira Pedro S. , Cunha Rodrigo A. , Sousa Nuno TITLE=Coffee consumption decreases the connectivity of the posterior Default Mode Network (DMN) at rest JOURNAL=Frontiers in Behavioral Neuroscience VOLUME=17 YEAR=2023 URL=https://www.frontiersin.org/journals/behavioral-neuroscience/articles/10.3389/fnbeh.2023.1176382 DOI=10.3389/fnbeh.2023.1176382 ISSN=1662-5153 ABSTRACT=

Habitual coffee consumers justify their life choices by arguing that they become more alert and increase motor and cognitive performance and efficiency; however, these subjective impressions still do not have a neurobiological correlation. Using functional connectivity approaches to study resting-state fMRI data in a group of habitual coffee drinkers, we herein show that coffee consumption decreased connectivity of the posterior default mode network (DMN) and between the somatosensory/motor networks and the prefrontal cortex, while the connectivity in nodes of the higher visual and the right executive control network (RECN) is increased after drinking coffee; data also show that caffeine intake only replicated the impact of coffee on the posterior DMN, thus disentangling the neurochemical effects of caffeine from the experience of having a coffee.