AUTHOR=Houser Troy M. 

TITLE=Spatialization of Time in the Entorhinal-Hippocampal System

JOURNAL=Frontiers in Behavioral Neuroscience

VOLUME=15

YEAR=2022

URL=https://www.frontiersin.org/journals/behavioral-neuroscience/articles/10.3389/fnbeh.2021.807197

DOI=10.3389/fnbeh.2021.807197

ISSN=1662-5153

ABSTRACT=<p>The functional role of the entorhinal-hippocampal system has been a long withstanding mystery. One key theory that has become most popular is that the entorhinal-hippocampal system represents space to facilitate navigation in one’s surroundings. In this Perspective article, I introduce a novel idea that undermines the inherent uniqueness of spatial information in favor of time driving entorhinal-hippocampal activity. Specifically, by spatializing events that occur in succession (i.e., across time), the entorhinal-hippocampal system is critical for all types of cognitive representations. I back up this argument with empirical evidence that hints at a role for the entorhinal-hippocampal system in non-spatial representation, and computational models of the logarithmic compression of time in the brain.</p>