AUTHOR=Lee Hongjoo J. , Haberman Rebecca P. , Roquet Rheall F. , Monfils Marie-H. TITLE=Extinction and Retrieval + Extinction of Conditioned Fear Differentially Activate Medial Prefrontal Cortex and Amygdala in Rats JOURNAL=Frontiers in Behavioral Neuroscience VOLUME=9 YEAR=2016 URL=https://www.frontiersin.org/journals/behavioral-neuroscience/articles/10.3389/fnbeh.2015.00369 DOI=10.3389/fnbeh.2015.00369 ISSN=1662-5153 ABSTRACT=
Pairing a previously neutral conditioned stimulus (CS; e.g., a tone) to an aversive unconditioned stimulus (US; e.g., a footshock) leads to associative learning such that the tone alone comes to elicit a conditioned response (e.g., freezing). We have previously shown that an extinction session that occurs within the reconsolidation window (termed retrieval + extinction) attenuates fear responding and prevents the return of fear in Pavlovian fear conditioning (Monfils et al.,