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ORIGINAL RESEARCH article

Front. Artif. Intell.

Sec. Medicine and Public Health

Volume 8 - 2025 | doi: 10.3389/frai.2025.1563016

This article is part of the Research Topic The Applications of AI Techniques in Medical Data Processing View all 3 articles

An Efficient Method for Early Alzheimer's Disease Detection based on MRI images using Deep Convolutional Neural Networks

Provisionally accepted
  • Department of Computer Science, College of Computing and Information Technology, Shaqra University, Saudi Arabia, Shaqra University, Shaqraa, Saudi Arabia

The final, formatted version of the article will be published soon.

    Alzheimer's disease (AD) is a progressive, incurable neurological disorder that leads to a gradual decline in cognitive abilities. Early detection is vital for alleviating symptoms and improving patient quality of life. With a shortage of medical experts, automated diagnostic systems are increasingly crucial in healthcare, reducing the burden on providers and enhancing diagnostic accuracy. AD remains a global health challenge, requiring effective early detection strategies to prevent its progression and facilitate timely intervention. In this study, a deep convolutional neural network (CNN) architecture is proposed for AD classification. The model, consisting of 6,026,324 parameters, uses three distinct convolutional branches with varying lengths and kernel sizes to improve feature extraction. The OASIS dataset used includes 80000 MRI images sourced from Kaggle, categorized into four classes: non-demented (67200 images), very mild demented (13700 images), mild demented (5200 images), and moderate demented (488 images). To address the dataset imbalance, a data augmentation technique was applied. The proposed model achieved a remarkable 99.68% accuracy in distinguishing between the four stages of Alzheimer's: Non-Dementia, Very Mild Dementia, Mild Dementia, and Moderate Dementia. This high accuracy highlights the model's potential for real-time analysis and early diagnosis of AD, offering a promising tool for healthcare professionals.

    Keywords: CNN, Alzheimer's disease (AD), deep learning, Early detection, MRI

    Received: 18 Jan 2025; Accepted: 24 Mar 2025.

    Copyright: © 2025 Dardouri. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Samia Dardouri, Department of Computer Science, College of Computing and Information Technology, Shaqra University, Saudi Arabia, Shaqra University, Shaqraa, Saudi Arabia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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