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ORIGINAL RESEARCH article

Front. Anim. Sci.
Sec. Animal Nutrition
Volume 5 - 2024 | doi: 10.3389/fanim.2024.1491519

Dietary glucose oxidase supplementation improves growth performance, intestinal morphology, and microbial community of broilers

Provisionally accepted
Xin Zhu Xin Zhu *Xinjie Zhang Xinjie Zhang Yong Zhang Yong Zhang Yujing Zhu Yujing Zhu Fangfang Li Fangfang Li
  • Shenyang Agricultural University, Shenyang, China

The final, formatted version of the article will be published soon.

    The objective of this study was to evaluate the influences of dietary glucose oxidase (GOD) supplementation in the growth and slaughter performance, organ index, intestinal morphology and cecal microbiota in broilers. A total of 480 one-day-old Arbor Acres male broiler chicks were randomly assigned to four groups, and the level of GOD in the diet was 0 (control), 200, 400, and 800 mg/kg. Each group had six replicates and each replicate had 20 chicks. The experimental period was 42 days. Compared to those in the control, the final body weight (BW) and average daily gain (ADG) were increased (p < 0.05) and the feed conversion ratio (FCR) was decreased (p < 0.05) in the 400 mg/kg and 800 mg/kg GOD groups. Dietary supplementation with 800 mg/kg GOD increased (p < 0.05) the dressing-out percentage; semieviscerated yield; relative weights of the thymus, spleen and bursa of Fabricius; and the lengths and weights of the duodenum, jejunum, ileum, and total small intestine compared to those in the control group. Additionally, dietary supplementation with GOD increased (p < 0.05) the villus height and villus height/crypt depth ratio and decreased (p < 0.05) the crypt depth of the duodenum and ileum compared to those of the control group. Illumina sequencing data indicated that the Simpson index of the cecal microbiota in the GOD group was decreased, indicative of increased microbial diversity. Compared to the control, GOD supplementation increased (p < 0.05) the abundances of the genera Ralstonia, Akkermansia and Parabacteroides. Therefore, the results from this study indicated that dietary GOD supplementation could improve the growth performance and carcass yields, promote immune organ and gut development, and enhance the intestinal morphology and cecal microbiota composition in broilers.

    Keywords: Glucose Oxidase, broiler, growth performance, gut health, microbiota

    Received: 05 Sep 2024; Accepted: 20 Nov 2024.

    Copyright: © 2024 Zhu, Zhang, Zhang, Zhu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xin Zhu, Shenyang Agricultural University, Shenyang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.