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CASE REPORT article

Front. Anesthesiol.

Sec. Perioperative Medicine

Volume 4 - 2025 | doi: 10.3389/fanes.2025.1554730

Case Report: Complications of an interscalene block with liposomal local anesthetic resulting in ICU Admission for over 25 days-Critical Sequelae of Outpatient surgical procedures

Provisionally accepted
  • 1 United States Air Force, Washington, United States
  • 2 Michigan Medicine, University of Michigan, Ann Arbor, Michigan, United States

The final, formatted version of the article will be published soon.

    Interscalene blockade is a widely accepted regional analgesic technique that has been demonstrated to limit postoperative pain and opioid consumption in total shoulder arthroplasty. Phrenic nerve paresis is an unintended consequence of this block and well tolerated in most patients. Development of liposomal bupivacaine (LB) offers potential extended duration analgesia over standard bupivacaine. FDA approval for the use of one specific preparation of LB for interscalene block was obtained in 2018 and research is ongoing as to the analgesic duration, benefits and side e effect profile of this relatively new local anesthetic (2).

    Keywords: Interscalene analgesia, Phrenic nerve palsy, Unanticipated admission, post-operative complication, Bupivacaine

    Received: 02 Jan 2025; Accepted: 26 Mar 2025.

    Copyright: © 2025 Byrne, Anderson and Meral. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Matthew Byrne, United States Air Force, Washington, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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