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ORIGINAL RESEARCH article

Front. Anal. Sci.
Sec. Environmental Analysis
Volume 4 - 2024 | doi: 10.3389/frans.2024.1506786

Cyclodextrin-assisted fluorescein decoration of gold nanoclusters for ratiometric and selective Hg 2+ analysis

Provisionally accepted
Siyuan Sun Siyuan Sun Zhiqin Yuan Zhiqin Yuan *
  • Beijing University of Chemical Technology, Beijing, China

The final, formatted version of the article will be published soon.

    The construction of nanomaterial-based ratiometric detection systems usually requires covalent modification, which undergoes reactive environments and may changes the natural properties of supporting nanomaterials. In this study, dual-emissive and fluorescein-decorated gold nanoclusters (F-Au NCs) through cyclodextrin-supported host-guest interaction (non-covalent modification), have been explored as the ratiometric Hg 2+ nanoprobes through d 10 -d 10 interaction caused fluorescence quenching of Au NCs. The fluorescein decoration only provides a fluorescent internal reference, but not changes the Hg 2+ -Au NCs affinity nature. Ratiometric and selective Hg 2+ detection is achieved through the proposed F-Au NCs probes with a limit of detection of 15 nM. The Hg 2+ analysis in river water samples with small relative standard deviations validates the practical application of proposed F-Au NCs probes.

    Keywords: Ratiometric fluorescence, Gold nanoclusters, Hg 2+ detection, d 10 -d 10 interaction, host-guest interaction

    Received: 06 Oct 2024; Accepted: 19 Dec 2024.

    Copyright: © 2024 Sun and Yuan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhiqin Yuan, Beijing University of Chemical Technology, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.