AUTHOR=Lyly Annina , Sahlman Johanna , Pajala Karoliina , Salminen Maija , Sillanpää Saara , Numminen Jura , Hanif Tanzeela , Laulajainen-Hongisto Anu , Mäkelä Mika , Kauppi Paula , Kangasniemi Iiris , Lilja Markus , Hammaren-Malmi Sari , Virkkula Paula , Toppila-Salmi Sanna TITLE=Study protocol for a randomized double-blinded placebo-controlled trial on mepolizumab for patients with chronic rhinosinusitis with nasal polyps, NSAID exacerbated respiratory disease and asthma JOURNAL=Frontiers in Allergy VOLUME=6 YEAR=2025 URL=https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2025.1568081 DOI=10.3389/falgy.2025.1568081 ISSN=2673-6101