AUTHOR=Guyénard Loris , Tauber Marie , Debord-Peguet Sophie , Berard Frédéric , Nosbaum Audrey , Hacard Florence , Castells Mariana , Nicolas Jean-François 

TITLE=Case Report: Mast cell anergy: absence of symptoms after accidental re-exposure to amoxicillin/clavulanic acid 3 days after anaphylaxis

JOURNAL=Frontiers in Allergy

VOLUME=5

YEAR=2024

URL=https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2024.1366922

DOI=10.3389/falgy.2024.1366922

ISSN=2673-6101

ABSTRACT=<p>Empty mast cell syndrome, also named post anaphylaxis mast cell anergy (PAMA), is a temporary state of loss of mast cell responsiveness after a severe immediate hypersensitivity reaction. In this study, we describe a case of PAMA after accidental re-exposure to amoxicillin in a patient who developed severe anaphylaxis to this drug three days earlier in the operating room. To our knowledge, this report is the second to document this phenomenon.</p>