AUTHOR=Phua Teow J. TITLE=Hallmarks of aging: middle-aging hypovascularity, tissue perfusion and nitric oxide perspective on healthspan JOURNAL=Frontiers in Aging VOLUME=5 YEAR=2025 URL=https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2024.1526230 DOI=10.3389/fragi.2024.1526230 ISSN=2673-6217