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REVIEW article

Front. Aging
Sec. Genetics, Genomics and Epigenomics of Aging
Volume 5 - 2024 | doi: 10.3389/fragi.2024.1395649
This article is part of the Research Topic Aging Epigenome and Longevity View all articles

New insights into methods to measure biological age: A literature review

Provisionally accepted
Sfoug Alshammary Sfoug Alshammary *Aanchal Mathur Aanchal Mathur Sebastien Taurin Sebastien Taurin
  • Arabian Gulf University, Manama, Bahrain

The final, formatted version of the article will be published soon.

    Biological age is a concept that reflects the physiological state of an individual rather than the chronological time since birth. It can help assess the risk of age-related diseases and mortality and the effects of interventions to slow down or reverse aging. However, there is no consensus on measuring biological age best, and different methods may yield different results. In this paper, which includes 140 relevant pieces of literature, out of 33000, we review some new methods to measure biological age based on recent advances in biotechnology and data science. We discussed some novel biomarkers and algorithms that can capture the dynamic and multidimensional aspects of aging at different levels. We evaluate their performance and validity using various datasets and criteria and compare them with existing methods. We also discuss their potential applications and implications for aging research and clinical practice. We conclude that the new methods offer more accurate and reliable estimates of biological age and open new avenues for understanding and modulating the aging process.

    Keywords: biological age, Epigenetic age, Exosomes, microbiome, Chronologic age

    Received: 04 Mar 2024; Accepted: 11 Nov 2024.

    Copyright: © 2024 Alshammary, Mathur and Taurin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Sfoug Alshammary, Arabian Gulf University, Manama, Bahrain

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.