AUTHOR=Cao Wei 

TITLE=IFN-Aging: Coupling Aging With Interferon Response

JOURNAL=Frontiers in Aging

VOLUME=3

YEAR=2022

URL=https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2022.870489

DOI=10.3389/fragi.2022.870489

ISSN=2673-6217

ABSTRACT=<p>Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Herein, we connote the mechanisms behind this phenomenon and discuss its implications in age-related pathology.</p>