Frontiers in Aging Neuroscience

Original Research

Published on 07 Feb 2025

Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

Shumin Zhao
Ranran Chen
Yi An
Yali Zhang
Cheng Ma
Ying Gao
Yanchao Lu
Fei Yang
Xue Bai
Jingjing Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522073

1,271 views

Correction

Published on 07 Feb 2025

Corrigendum: Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review

in Alzheimer's Disease and Related Dementias

Jiangfeng Liao
Wenming Hu
Shiheng Chen
Chunyu Huang
Senwei Dong
Wanjin Chen
Xiaochun Chen
Longfei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565464

1,017 views

Original Research

Published on 07 Feb 2025

Higher systemic immune-inflammation index is associated with increased risk of Parkinson’s disease in adults: a nationwide population-based study

in Parkinson’s Disease and Aging-related Movement Disorders

Jiayu Zhao
Zhipeng Wu
Fengyin Cai
Xuejv Yu
Zhenyu Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529197

1,629 views

Original Research

Published on 07 Feb 2025

Brain compensatory activation during Stroop task in patients with mild cognitive impairment: a functional near-infrared spectroscopy study

in Neurocognitive Aging and Behavior

Chenyu Fan
Hanfei Li
Ke Chen
Guohui Yang
Hongyu Xie
Haozheng Li
Yi Wu
Meng Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1470747

1,129 views
2 citations

Original Research

Published on 07 Feb 2025

Association between carotid artery hemodynamics and neurovascular coupling in cerebral small vessel disease: an exploratory study

in Neurocognitive Aging and Behavior

Peng Zeng
Bang Zeng
Xiaohua Wang
Feiyue Yin
Binglan Li
Lisha Nie
Lin Tian
Dan Luo
Yongmei Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536552

1,268 views

Original Research

Published on 05 Feb 2025

Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study

in Neurocognitive Aging and Behavior

Chunhui Zhou
Ganfeng Yang
Marc Theeboom
Hua Yang
Ruiting Zhu
Zijian Zhou
Dong Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505815

1,316 views

Systematic Review

Published on 05 Feb 2025

A systematic review of the efficacy of repetitive transcranial magnetic stimulation in treating dysarthria in patients with Parkinson's disease

in Neurocognitive Aging and Behavior

Kerong Chen
Sitong Zhou
Shiyu Lu
Yuliang Qin
Xinyao Li
Yi Li
Tianyun Liu
Mei Zhang
Kun Xu
Hongping Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1501640

1,240 views

Mini Review

Published on 05 Feb 2025

A synthesized view of the CSF-blood barrier and its surgical implications for aging disorders

in Cellular and Molecular Mechanisms of Brain-aging

Birra Taha
Robert McGovern
Cornelius Lam

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1492449

1,046 views

Original Research

Published on 05 Feb 2025

Sex-specific associations between estimated glucose disposal rate and cognitive decline in middle-aged and older adults in China: a longitudinal cohort study

in Neurocognitive Aging and Behavior

Chun Luo
Shuang Han
Xiaoying Shen
Hao Wu
Jianqing Zhou
Bingyang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1544352

1,623 views

Original Research

Published on 04 Feb 2025

Auditory steady state response can predict declining EF in healthy elderly individuals

in Neurocognitive Aging and Behavior

Xiaopeng Mao
Nelly Shenton
Sadasivan Puthusserypady
Martin Johannes Lauritzen
Krisztina Benedek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516932

1,013 views

Original Research

Published on 04 Feb 2025

Association between hemoglobin glycation index and poor outcome after endovascular thrombectomy in acute ischemic stroke

in Neuroinflammation and Neuropathy

Yan Yang
Mei Liu
Shungui Huang
Chen Zhu
Guangzong Li
Bin Wang
Xiaojing Luo
Lingwen Zhang
Weizheng Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1533584

1,300 views

Original Research

Published on 04 Feb 2025

Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yan Wu
Narayan R. Bhat
Meng Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529769

1,471 views

Original Research

Published on 04 Feb 2025

Investigating dynamic brain functional redundancy as a mechanism of cognitive reserve

in Neurocognitive Aging and Behavior

Julia Schwarz
Franziska Zistler
Adriana Usheva
Anika Fix
Sebastian Zinn
Juliana Zimmermann
Franziska Knolle
Gerhard Schneider
Rachel Nuttall

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535657

1,148 views

Original Research

Published on 04 Feb 2025

Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach

in Parkinson’s Disease and Aging-related Movement Disorders

Yifeng Yang
Liangyun Hu
Yang Chen
Weidong Gu
Guangwu Lin
YuanZhong Xie
Shengdong Nie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1510192

1,692 views

Original Research

Published on 03 Feb 2025

Nomogram for predicting mild cognitive impairment in Chinese elder CSVD patients based on Boruta algorithm

in Alzheimer's Disease and Related Dementias

Yanzi Huang
Wendie Huang
Xiaoming Ma
Guoyin Zhao
Jingwen Kang
Huajie Li
Jingwei Li
Shiying Sheng
Fengjuan Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1431421

1,196 views

Original Research

Published on 03 Feb 2025

Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Alexa L. Wright
Aldis P. Weible
Olivia B. Estes
Michael Wehr

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505908

1,314 views