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ORIGINAL RESEARCH article

Front. Aging Neurosci.
Sec. Neurocognitive Aging and Behavior
Volume 16 - 2024 | doi: 10.3389/fnagi.2024.1507285
This article is part of the Research Topic Progress in the Assessment and Intervention of Neurocognitive Aging and Neurodegenerative Diseases View all 4 articles

Sleep structure of short-term insomnia disorder with mild cognitive impairment in older adults and their correlation with cognitive function: a case-control study

Provisionally accepted
Jinkun Zeng Jinkun Zeng Wei Jia Wei Jia Ruobing Qi Ruobing Qi *
  • Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China

The final, formatted version of the article will be published soon.

    Objectives: This study seeks to delineate the sleep architecture characteristics in older adults with short-term insomnia and mild cognitive impairment (MCI) and to explore their association with cognitive performance.: Ninety elderly individuals with short-term insomnia were enrolled and stratified into two cohorts based on their Montreal Cognitive Assessment (MoCA) scores: the Short-Term Insomnia Group (STID) comprising 35 participants and the Short-Term Insomnia with Cognitive Impairment Group (STID-MCI) with 55 participants. Demographic data, Pittsburgh Sleep Quality Index (PSQI), MoCA, Hamilton Depression Rating Scale (HAMD-17), Hamilton Anxiety Rating Scale (HAMA), and polysomnography (PSG) parameters were compared between groups. Correlations between MoCA scores and PSG metrics were also analyzed.Results: No significant disparities were noted between groups in terms of HAMD-17, HAMA, and PSQI scores (P > 0.05). However, marked differences were identified in MoCA scores and its subdomains (P < 0.05). Significant variations were also observed in the duration and proportion of slow-wave sleep (N3) between groups (P < 0.05). In STID-MCI patients, memory scores correlated positively with N3 duration and percentage (P < 0.05), while verbal functions and attention were positively associated with rapid eye movement (REM) sleep duration.Conclusions：This study highlights the potential of PSG in the clinical assessment of cognitive function and underscores the need for targeted interventions to improve sleep quality in this vulnerable population.

    Keywords: Short-term Insomnia Disorder, Mild Cognitive Impairment, Polysomnography, older adults, case-control study

    Received: 07 Oct 2024; Accepted: 26 Nov 2024.

    Copyright: © 2024 Zeng, Jia and Qi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ruobing Qi, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China

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