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BRIEF RESEARCH REPORT article

Front. Aging Neurosci.
Sec. Alzheimer's Disease and Related Dementias
Volume 16 - 2024 | doi: 10.3389/fnagi.2024.1465812
This article is part of the Research Topic Mental, Sensory, Physical and Life Style Parameters Related to Cognitive Decline in Aging View all 14 articles

The bidirectional relationship between subjective visual function and domain-specific cognition in cognitively unimpaired older adults and adults with mild cognitive impairment

Provisionally accepted
Abigail Dubois Abigail Dubois 1Jordan Sergio Jordan Sergio 1Sima Mozdbar Sima Mozdbar 2Ashley Price Ashley Price 1,3Megan Stradtman Megan Stradtman 3,4Louisa Thompson Louisa Thompson 3,4Peter Jeffrey Snyder Peter Jeffrey Snyder 1Jessica Alber Jessica Alber 1,3*
  • 1 University of Rhode Island, Kingston, Rhode Island, United States
  • 2 School of Medicine, Texas Christian University, Fort Worth, Texas, United States
  • 3 Butler Hospital, Providence, Rhode Island, United States
  • 4 Warren Alpert Medical School, Brown University, Providence, Rhode Island, United States

The final, formatted version of the article will be published soon.

    INTRODUCTION: Subjective visual impairment (VI) is related to cognition in cognitively unimpaired (CU) older adults, mild cognitive impairment (MCI) patients, and Alzheimer's disease (AD) patients. The utility of subjective VI as an indicator for domain-specific cognitive impairment is unknown.We used the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25 item) and a neuropsychological battery to assess the relationship between subjective VI and domain-specific cognitive performance in CU older adults (N=58) and MCI patients (N=16).The CU group showed a positive relationship between subjective VI and visuospatial performance. CU older adults at high risk for AD demonstrated a unique relationship between subjective VI and attention, processing speed, and executive function. Peripheral vision was related to domain-specific performance in the patient group. DISCUSSION: Subjective VI complaints may indicate potential for domain-specific cognitive decline in visuospatial performance, executive function, processing speed, and attention in older adults.

    Keywords: visual function, Aging, Domain-specific cognition, Mild Cognitive Impairment, Alzheimer's disease, Preclinical Alzheimer's disease

    Received: 16 Jul 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 Dubois, Sergio, Mozdbar, Price, Stradtman, Thompson, Snyder and Alber. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jessica Alber, University of Rhode Island, Kingston, 02881, Rhode Island, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.