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REVIEW article
Front. Aging Neurosci.
Sec. Neuroinflammation and Neuropathy
Volume 16 - 2024 |
doi: 10.3389/fnagi.2024.1446523
Mechanisms Underlying Delirium in Patients with Critical Illness
Provisionally accepted- 1 Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China
- 2 Zhejiang Provincial People's Hospital, Hangzhou, China
Delirium is an acute, global cognitive disorder syndrome, also known as acute brain syndrome, characterized by disturbance of attention and awareness and fluctuation of symptoms. Its incidence is high among critically ill patients.Once patients develop delirium, it increases the risk of unplanned extubation, prolongs hospital stay, increases the risk of nosocomial infection, post-intensive care syndrome-cognitive impairment, and even death.Therefore, it is of great importance to understand how delirium occurs and to reduce the incidence of delirium in critically ill patients.This paper reviews the potential pathophysiological mechanisms of delirium in critically ill patients, with the aim of better understanding its pathophysiological processes, guiding the formulation of effective prevention and treatment strategies, providing a basis for clinical medication.
Keywords: Delirium1, Critical illness2, Cognition impairment3, Mechanism4, Review5 Conceptualization,Investigation,Interpretation of data,Writing &Revising draft,Draw a figure, Author LRY:Conceptualization,Investigation,Writing -Original Draft, Author WMT:Conceptualization,Investigation,Writing -Original Draft, Author YCY:Conceptualization,Investigation,Revising draft, Author SYY:Conceptualization,Investigation,Draw a figure, Conceptualization,Supervision, Writing -Review & Editing
Received: 10 Jun 2024; Accepted: 09 Sep 2024.
Copyright: © 2024 Fan, Luo, Wang, Yuan, Sun and Jing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jiyong Jing, Zhejiang Provincial People's Hospital, Hangzhou, China
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