Skip to main content

SYSTEMATIC REVIEW article

Front. Aging Neurosci.
Sec. Parkinson’s Disease and Aging-related Movement Disorders
Volume 16 - 2024 | doi: 10.3389/fnagi.2024.1419643
This article is part of the Research Topic Effectiveness of Exercise and Diet on Movement Disorders View all 8 articles

The impact of aerobic exercise dose based on ACSM recommendations on patients with Parkinson's disease: A systematic review and metaanalysis of randomized controlled trials

Provisionally accepted
Cui Wenlai Cui Wenlai 1*Jian Li Jian Li 1Zepeng Hu Zepeng Hu 1Siji Wang Siji Wang 1Ruilin Xu Ruilin Xu 2*
  • 1 Capital Institute of Physical Education and Sports, Beijing, China
  • 2 Zhengzhou University, Zhengzhou, Henan Province, China

The final, formatted version of the article will be published soon.

    Background: To explore the effects of different dose of aerobic exercise on motor function, balance, mobility, and quality of life in Parkinson's disease patients, aiming to provide insights into determining the optimal aerobic exercise dose for treating PD.Methods: Searching was conducted in four databases: PubMed, Embase, Web of Science, and Cochrane. The dose of aerobic exercise intervention was evaluated based on the recommendations of the American College of Sports Medicine regarding the development and maintenance of cardiorespiratory health, muscle strength, and functional mobility in patients with PD. The exercise intervention dose of the included studies were first classified into high ACSM compliance and low ACSM compliance based on meeting 4/6 of the ACSM recommendations. The reliability of the results was then validated using the criterion of meeting 5/6 of the ACSM recommendations.Comparisons of the effects of aerobic exercise dose on Motor function, Balance, Mobility, and QOL in PD patients using standardized mean difference with 95% confidence intervals.Results: When using the 4/6 ACSM compliance criterion, 17 studies were categorized as high ACSM compliance and 12 as low ACSM compliance. The SMD ratios for high versus low ACSM compliance were: UPDRS-III (-0.79: -0.18), BBS (0.60: 0.05), TUG (-0.60: -0.60), and QOL (-1.05: -0.15). When using the 5/6 ACSM compliance criterion, 11 studies were categorized as high ACSM compliance and 19 as low ACSM compliance. The SMD ratios for high versus low ACSM compliance were: UPDRS-III (-0.95: -0.38), BBS (0.48: 0.37), TUG (-0.71: -0.55), and QOL (-0.7: 0.04). Conclusions: This study provides preliminary support for the potential of aerobic exercise to improve certain clinical symptoms in patients with PD. Furthermore, the results indicate that compliance to higher doses of aerobic exercise, as per ACSM standards, may contribute to improvements in motor function, balance, mobility, and quality of life for patients with PD. However, due to the heterogeneity in the studies and the influence of factors that have not yet been fully explored, these conclusions should be interpreted with caution. More high-quality randomized controlled trials are needed in the future to further verify and clarify the effects of aerobic exercise.

    Keywords: Parkinson's disease, aerobic exercise, Dose, ACSM Recommendation, metaanalysis

    Received: 18 Apr 2024; Accepted: 17 Sep 2024.

    Copyright: © 2024 Wenlai, Li, Hu, Wang and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Cui Wenlai, Capital Institute of Physical Education and Sports, Beijing, China
    Ruilin Xu, Zhengzhou University, Zhengzhou, 450001, Henan Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.