AUTHOR=Sun Jin , Ma Xiaobao , Yang Ying , He Kuan , Wang Wei , Shen Jiali , Wang Lu , Chen Xiangping , Jin Yulian , Yang Jun , Chen Jianyong 

TITLE=Associations between cognition, anxiety, depression, and residual dizziness in elderly people with BPPV

JOURNAL=Frontiers in Aging Neuroscience

VOLUME=15

YEAR=2023

URL=https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2023.1208661

DOI=10.3389/fnagi.2023.1208661

ISSN=1663-4365

ABSTRACT=<sec><title>Objective</title><p>To investigate the associations between cognition, anxiety, depression, and residual dizziness after successful repositioning maneuvers in the elderly with benign paroxysmal positional vertigo (BPPV).</p></sec><sec><title>Methods</title><p>We enrolled 40 elderly patients with BPPV in our outpatient department. We used the Dizziness Handicap Inventory (DHI), Visual Analog Scale (VAS), Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder Questionnaire-7 (GAD-7) to assess the degree of dizziness, anxiety, and depression of participants before repositioning therapy, respectively. At the 1-week follow-up after BPPV treatment, each participant will be reassessed and divided into a group with residual dizziness (RD) and a group without residual dizziness (NRD) based on the follow-up DHI score. The Mini-Mental State Examination (MMSE) evaluated the cognitive function of the participants.</p></sec><sec><title>Results</title><p>The age, gender, duration of BPPV, and involved semicircular canals in the two groups did not show a significant difference. The RD group scored significantly higher on the DHI (<italic>p</italic> = 0.006), GAD-7 (<italic>p</italic> &lt; 0.001), and PHQ-9 (<italic>p</italic> = 0.002) before the repositioning treatment than the NRD group. The two groups had no significant difference in MMSE score (<italic>p</italic> = 0.381). Anxiety and depression scores before repositioning treatment significantly and positively correlated with follow-up DHI scores (<italic>r</italic> = 0.678 and 0.522, respectively), but the MMSE score did not significantly relate to it. The univariate linear regression showed that the DHI (<italic>p</italic> &lt; 0.001), GAD-7 (<italic>p</italic> &lt; 0.001), and PHQ-9 (<italic>p</italic> = 0.002) scores before treatment could predict residual dizziness. The multivariate linear regression showed that GAD-7 before treatment was the only significant predictor of residual dizziness (<italic>p</italic> &lt; 0.001).</p></sec><sec><title>Conclusion</title><p>The level of dizziness, anxiety, and depression before treatment can predict residual dizziness after successful repositioning maneuvers in the elderly with BPPV. Anxiety may be the strongest predictor of residual dizziness after successful repositioning treatment in elderly BPPV patients.</p></sec>