Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice
- Immunology of Cellular Receptors, Department of Molecular Immunology, Palladin Institute of Biochemistry, Kyiv, Ukraine
A Corrigendum on
Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice
by Lykhmus, O., Kalashnyk, O., Uspenska, K., and Skok, M. (2020). Front. Aging Neurosci. 11:359. doi: 10.3389/fnagi.2019.00359
In the original article, there was a mistake in Figure 1A as published. The list of groups shown in the figure should not be 1 to 5 but 2 to 6. The corrected Figure 1 appears below.
Figure 1. Episodic memory [Discrimination Index (DI)] of mice studied in the NOR test. (A) Mice were injected with lipopolysaccharide (LPS) and treated with PNU282 either immediately or 7 days after (groups 2–4, Table 1) or with PNU120 or PNU120+PNU282 immediately after LPS (groups 5–6); (B) mice were injected with LPS and treated with nicotine (group 7), or treated with PNU282 2 months after LPS injection (group 9). Each point on the curve corresponds to Mean ± SD, n = 5. **p < 0.005; ***p < 0.0005 compared to Day 0. For LPS 2m, Day 0 corresponds to 2 months after LPS injection.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: α7 nicotinic acetylcholine receptor, inflammation, brain, mitochondria, PNU282987, PNU120596
Citation: Lykhmus O, Kalashnyk O, Uspenska K and Skok M (2020) Corrigendum: Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice. Front. Aging Neurosci. 12:18. doi: 10.3389/fnagi.2020.00018
Received: 13 January 2020; Accepted: 20 January 2020;
Published: 06 February 2020.
Edited and reviewed by: Rubem C. A. Guedes, Federal University of Pernambuco, Brazil
Copyright © 2020 Lykhmus, Kalashnyk, Uspenska and Skok. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Maryna Skok, skok@biochem.kiev.ua