AUTHOR=Avila Jesus , Jiménez Juan S. , Sayas Carmen L. , Bolós Marta , Zabala Juan C. , Rivas Germán , Hernández Felix 

TITLE=Tau Structures

JOURNAL=Frontiers in Aging Neuroscience

VOLUME=8

YEAR=2016

URL=https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2016.00262

DOI=10.3389/fnagi.2016.00262

ISSN=1663-4365

ABSTRACT=<p>Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations.</p>