Toxicity profiling of natural products and druggable compounds: Where are we now?

Fareeha Anwar, Sarfraz Ahmad, Muhammad Furqan Akhtar, Tariq Ismail, Fawad Ali Shah, Arshad Mahmood

Frontiers Media SA

Science Pharmacology Predictive Toxicology

Keywords: toxicity profiling,­Toxicity studies,­acute toxicity,­Sub-acute toxicity,­developmental toxicity,­teratogenicity,­toxicity pathways,­Toxicity models,­biomarkers,­neurotransmitters

Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans, Volume II

Fatma Mohamady El-Demerdash, Alex Boye, Michel Mansur Machado, Yanzhu Zhu, Xinwei Li, Xu Yang

Frontiers Media SA

Science Pharmacology Predictive Toxicology

Keywords: Exposure,­toxicokinetics,­metal,­Toxicology,­Mechanism,­#CollectionSeries

Zebrafish as a Model for Pharmacological and Toxicological Research

Carla Denise Bonan, Anna Siebel

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Drug Discovery,­Toxicity,­Behavior,­development,­High-Throughput Screening

Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans

Yanzhu Zhu, Fatma Mohamady El-Demerdash, Xinwei Li, Michel Mansur Machado, Alex Boye

Frontiers Media SA

Science Pharmacology Predictive Toxicology

Keywords: Exposure,­toxicokinetics,­metal,­Toxicology,­Mechanism

Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond

Eleonora Grandi, Stefano Morotti, Esther Pueyo, Blanca Rodriguez

Frontiers Media SA

Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as...

Science Physiology Cardiac Electrophysiology

Keywords: cardiotoxicity,­QT interval prolongation,­Drug-induced arrhythmia,­Multi-scale modeling,­Cardiac Electrophysiology

EUFEMED 2017

Kerstin Breithaupt-Grögler, Ingrid Klingmann, Hildegard Sourgens, Michael Hammond, Ulrike Lorch, Jorg Taubel, Jan de Hoon, Luc Van Bortel, Henri Caplain, Yves Donazzolo, Tim Hardman, Steffan Stringer

Frontiers Media SA

EUFEMED CONFERENCE, London, UK 17 - 19 May 2017

EUFEMED 2017 is the 1st conference of...

Science Pharmacology Analytical and Experimental Pharmacology

Keywords: human pharmacology,­early phase drug development,­Risk Management,­over-volunteering,­patient recruitment,­Exploratory clinical trials