New Insights into Intracellular Pathways and Therapeutic Targets in CNS Diseases

Lisa Gherardini, Eleonora Vannini, Mario Chiariello, Anna Lisa Iorio, Orazio Santo Santonocito

Frontiers Media SA

The intracellular signalling network machinery, responding to different micro-environmental cues,...

Science Cellular Neuroscience Cellular Neurophysiology

Keywords: cell signalling,­Prognostic biomarkers,­new therapies,­Neuro Pharmacoepidemiology,­CNS disorders

SENSORY HAIR CELL DEATH AND REGENERATION, 2nd Edition

Michael E. Smith, Andrew K. Groves, Allison B. Coffin

Frontiers Media SA

Sensory hair cells are the mechanosensory receptors of the auditory and vestibular systems in all...

Science Cellular Neuroscience Cellular Neuropathology

Keywords: Mechanosensory receptors,­Hair cell death,­Regeneration

Mechanisms of Neurodegeneration in Amyotrophic Lateral Sclerosis and Related Disorders

Danyllo Oliveira, Agnes Lumi Nishimura

Frontiers Media SA

Motor neuron diseases (MNDs) comprise a large and heterogeneous group of disorders in which the...

Science Cellular Neuroscience Cellular Neuropathology

Keywords: Amyotrophic Lateral Sclerosis,­neurodegeneration,­genetic risk factor,­Mendelian randomization,­Disease mechanisms,­spinal muscular atrophy,­Myopathy

Stem cell-derived retinal and brain organoid culture for disease modeling

Lin Cheng, Carla Mellough, Kin-Sang Cho, Maeve Ann Caldwell

Frontiers Media SA

Science Cellular Neuroscience Cellular Neuropathology

Keywords: Stem Cells,­retinal organoids,­brain/CNS/cerebral organoids,­Neurodegenerative Diseases,­disease modeling

Morphogens in the Wiring of the Nervous System

Juan Pablo Henríquez, Nelson Osses

Frontiers Media SA

Neuronal function relies on the establishment of proper connections between neurons and their...

Science Cellular Neuroscience Non-Neuronal Cells

Keywords: Morphogens,­Neuroscience,­Cells,­Nervous System,­Neurons,­Target cells

Inhibitory interneuron classification, function and dysfunction in neural network

Thomas Claude Bienvenu, Norbert Hajos, Frederic Lanore

Frontiers Media SA

Health Psychiatry

Keywords: GABAergic interneuron subtypes,­Learning,­Memory,­Cognition,­synaptic plasticity,­Systems neuroscience,­Neuropsychiatry

Oligodendrocytes: From Their Development to Function and Dysfunction

Hiroaki Wake, Shingo Miyata

Frontiers Media SA

Oligodendrocytes are key non-neuronal cells that are generated from oligodendrocyte progenitor...

Science Cellular Neuroscience Non-Neuronal Cells

Crosstalk between Peripheral and Local Immune Response in the Pathophysiology of Stroke and Neurodegeneration Diseases, Volume II

Yuanjian Fang, Lei Huang, Xiangsheng Zhang, Anwen Shao, Dirk M. Hermann

Frontiers Media SA

Accumulating evidence reveals both local and peripheral immune systems participated in the...

Science Cellular Neuroscience Cellular Neuropathology

Keywords: peripheral immune response,­Local immune response,­Stroke,­Alzheimer’s disease,­Parkinson’s disease,­Amyotrophic Lateral Sclerosis

Restoring Functional Behaviors After Traumatic Peripheral Nerve Injuries

George Davis Bittner, Jared Bushman, Jaimie Shores, Joseph Alderete, Dale Sengelaub

Frontiers Media SA

Peripheral nerve injuries (PNIs) by trauma are the most common neuronal injury in civilian and...

Science Cellular Neuroscience Cellular Neuropathology

Keywords: Axotomy,­Wallerian Degeneration,­Allografts,­Autografts,­never conduits,­axonal regeneration