Genomics and Epigenomics of Cancer Immunotherapy: Challenges and Clinical Implications, 3rd edition

Xiao-Jie Lu, Malak Abedalthagafi, Xiaochen Wang

Frontiers Media SA

Cancer immunotherapy aims to activate, boost or normalize the immune system to attack cancer cells...

Health Oncology

Keywords: Antitumor immunogenicity,­personalized biomarkers,­Immunotherapy combinations,­preclinical models,­Immune cell dysfunction

Oncogenic PI3KT/Akt/mTOR Pathway Alterations, ROS Homeostasis, Targeted Cancer therapy and drug resistance, 2nd edition

Rozangela Curi Pedrosa, Karina Felipe, Danilo Wilhelm Filho

Frontiers Media SA

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin...

Health Oncology

Keywords: PI3KT,­Akt,­mTOR,­Metabolism,­Reactive Oxygen Species

Allogenic Hematopoietic Cell Transplant in Hematological Malignancies: Controversies and Perspective

Salvatore Leotta, Jacopo Mariotti, Sabrina Giammarco

Frontiers Media SA

The Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), since the experiments in rodents in...

Health Oncology Hematologic Malignancies

Keywords: Stem Cell Transplantation,­Acute leukemia,­graft versus host disease,­hematological malignancies,­Conditioning regimen

Exploring Oncolytic Virotherapy in Solid Tumor Treatment

Peng Qu, Guohao Wang, Yue Huang

Frontiers Media SA

Oncolytic virus therapy for solid tumor is an well-established concept as a promising tumor...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: oncolytic virus,­therapy,­Solid tumor,­combination therapeutics,­immune cells,­delivery system,­Engineered virus

KRAS in Stage IV Non-Small Cell Lung Cancer

Georgia Hardavella, Torsten Gerriet Blum, Wouter H. Van Geffen

Frontiers Media SA

The oncogenic impacts of the KRAS gene were first reported in the 1980s, making KRAS one of the...

Health Oncology Thoracic Oncology

Keywords: KRAS,­NSCLC,­lung cancer,­G12C,­Kirsten Rat Sarcoma

Circadian Rhythms and Cancer Hallmarks: Toward Advances in Immune-Based Therapeutics, and Outcomes

Elizabeth Cash, Sandra E. Sephton, Pasquale F. Innominato

Frontiers Media SA

Circadian rhythms are the daily fluctuations in physiological processes that govern cell cycles and...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: circadian,­Cancer,­immuno-oncology,­clock gene,­Cancer hallmarks,­Chronotherapy,­cancer therapeutics

Treatment Strategies for Head and Neck Cancer Confronting Cancer Through Multidisciplinary Collaboration

Tomoko Yamazaki, Tomoya Yokota, Jason Chia-Hsun Hsieh, Satoshi Saito

Frontiers Media SA

Regardless of the type of cancer, multidisciplinary collaboration is essential. Head and cancer...

Health Oncology Head and Neck Cancer

Keywords: head and neck cancer,­Multidisciplinary tea,­Multidisciplinary collaboration,­chemoradiation operation,­cancer treatment

Non-coding RNAs in Breast Cancer, volume II

Wenwen Zhang, Xiaoxiang Guan, Naoyuki Kataoka

Frontiers Media SA

Breast cancer (BC) is the most common malignancy among females worldwide. Breast cancer is a highly...

Health Oncology Cancer Genetics

Keywords: ncRNAs,­breast cancer,­prognosis,­diagnosis,­biomarkers

Deciphering the Regulatory Role of Transcription Factors in Cancer Immune Infiltration

Qian Yang, Yujia Lan, Jin-Fen Xiao

Frontiers Media SA

Transcription factors (TF) are proteins that bind to specific DNA sequences and regulate the...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: Transcription Factors,­Epigenetic regulator,­Tumor Microenvironment,­cancer immunology,­Immune infiltration,­tumor immune escape,­regulatory networks