Molecular Mechanisms of Cilia Related Diseases

Joao Goncalves, Sara Carvalhal, Anne-Marie Tassin, Bruno Carmona

Frontiers Media SA

Eukaryotic cilia are evolutionarily conserved microtubule-based structures that protrude from the...

Science Molecular Biosciences Molecular Biology

Keywords: "Cilia,­Genetics,­Therapeutics,­Cilia-related diseases

Molecular mechanisms underlying polycystic kidney disease: From the smallest bricks to the big scenario

Annarita Di Mise, Michael Caplan, Giovanna Valenti

Frontiers Media SA

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: mechanisms,­polycystic kidney disease,­molecular,­mutations,­Dominant,­Recessive

Progress and challenges in computational structure-based design and development of biologic drugs

Traian Sulea, Sandeep Kumar, Daisuke Kuroda

Frontiers Media SA

Science Molecular Biosciences Biological Modeling and Simulation

Keywords: biologics,­Antibodies,­Drug Development,­ab,­computational,­structural,­Structure,­monoclonal,­nanobodies

New Progress in Cancer Biomarkers and Therapy

Guohui Sun, Wei Zhang, Jianhua Wang, Chengwei He

Frontiers Media SA

As we know, cancer is an important disease threatening human health. According to the latest...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: Cancer biomarkers,­Biomarkers Discovery,­cancer diagnosis,­Cancer prognosis,­cancer therapy

Molecular Level Atomistic and Structural Insights on Biological Macromolecules, Inhibition, and Dynamics Studies

Chandrabose Selvaraj, Emilia Pedone, Jung-Kul Lee, Sanjeev Kumar Singh

Frontiers Media SA

Everything in a living organism relies on biological macromolecules, which have the role of...

Science Molecular Biosciences Molecular Biophysics

Keywords: enzyme kinetics,­Molecular dynamics methods,­molecular dynamics simulations,­Biological macromolecules,­Atomistic mechanism

Computational and Experimental Protein Variant Interpretation in the Era of Precision Medicine

Daniele Dell'Orco, Valerio Consalvi, Silvia Morante, Paola Turina, Tiziana Sanavia, Arthur M. Lesk, Constantina Bakolitsa

Frontiers Media SA

One of the key goals in the postgenomic era is the elucidation of the mechanisms underlying the...

Science Molecular Biosciences Protein Biochemistry for Basic and Applied Sciences

Keywords: computational,­experimental,­protein,­variant,­precision medicine

Reviews in Chemistry

Omotayo Ademola Arotiba, Xiao Xiao, Mohammad Mansoob Khan, Jun Chen, Kang Xiao, Tingchao He

Frontiers Media SA

We are delighted to present the second edition of the “Reviews in Chemistry*” article collection....

Science Materials

Preparation and Application of Intelligent Bioactive Nanocolloids

Yu Luo, Xin Li, Andrij Pich, Bo Yin

Frontiers Media SA

The major health and energy crises caused by environmental changes have always attracted attention,...

Science Materials

Mycobacteria and the Macrophage

Suzie Hingley-Wilson, Samantha Leigh Sampson, Sangeeta Tiwari

Frontiers Media SA

The macrophage (or “big eater”) is often considered the first cell type to encounter the causative...

Science Molecular Biosciences Molecular Biology

Keywords: Intracellular bacteria,­Mycobacterium tuberculosis complex (MTBC),­macrophage interactions,­macrophage,­Mycobacterium tuberculosis