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CASE REPORT article

Front. Vet. Sci.
Sec. Oncology in Veterinary Medicine
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1500679
This article is part of the Research Topic Cancer in Domestic, Exotic and Wild Animals: New Horizons in Tumorigenesis, Diagnosis, Prognosis and Therapeutics through Comparative Oncology View all 4 articles

Case Report: A Study on the Pathological Diagnosis of Oral Fibrosarcoma in a Giant Panda

Provisionally accepted
Zong-Liang Xiong Zong-Liang Xiong 1Shanshan Lin Shanshan Lin 2*Caiwu Li Caiwu Li 2*Linhua Deng Linhua Deng 2*He Ming He Ming 2Chengdong Wang Chengdong Wang 2*Desheng Li Desheng Li 2*Zhengli Chen Zhengli Chen 1*
  • 1 Sichuan Agricultural University, Cheng Du, China
  • 2 China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China

The final, formatted version of the article will be published soon.

    A female giant panda presented with a large, hard mass on the right cheek, which was investigated at the Dujiangyan Base of the China Conservation and Research Center for the Giant Panda with computed tomography (CT) scans and biopsy of the oral mass, as well as venous blood sampling. Hematological tests revealed elevated levels of the tumor marker CA724, along with infectious disease, anemia, hepatic damage, and renal failure. Imaging studies identified a soft tissue mass in the right cheek area. Macroscopic pathological changes, histopathological features, and immunohistochemical analysis were consistent with a low-grade malignant fibrosarcoma within the oral cavity, indicating malignant potential. This case represents the first report of an oral tumor in a giant panda, providing valuable data for future clinical diagnoses of neoplasms in this species.

    Keywords: case report, giant panda, Oral fibrosarcoma, Pathology diagnostic research, Biopsy

    Received: 23 Sep 2024; Accepted: 16 Dec 2024.

    Copyright: © 2024 Xiong, Lin, Li, Deng, Ming, Wang, Li and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Shanshan Lin, China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China
    Caiwu Li, China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China
    Linhua Deng, China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China
    Chengdong Wang, China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China
    Desheng Li, China Conservation and Research Center for the Giant Panda,Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in the Giant Panda National Park, Cheng Du, China
    Zhengli Chen, Sichuan Agricultural University, Cheng Du, China

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