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REVIEW article

Front. Vet. Sci.
Sec. Parasitology
Volume 11 - 2024 | doi: 10.3389/fvets.2024.1413237
This article is part of the Research Topic African swine fever virus (ASFV) in the one health approach View all 4 articles

African swine fever; insights into genomic aspects, reservoirs and transmission patterns of virus

Provisionally accepted
Bader Alotaibi Bader Alotaibi 1Chia-Hung Wu Chia-Hung Wu 2Majid Khan Majid Khan 3Mohsin Nawaz Mohsin Nawaz 4Chien-Chin Chen Chien-Chin Chen 2Abid Ali Abid Ali 3*
  • 1 Shaqra University, Shaqraa, Riyadh, Saudi Arabia
  • 2 Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan
  • 3 Abdul Wali Khan University Mardan, Mardan, Pakistan
  • 4 University of Poonch Rawalakot, Rawalakot, Azad Kashmir, Pakistan

The final, formatted version of the article will be published soon.

    African swine fever is a hemorrhagic disease of pigs with high mortality rates. Since its first characterization in 1921, there has been sufficient information about African swine fever virus (ASFV) and related diseases. The virus has been found and maintained in the sylvatic cycle involving ticks and domestic and wild boars in affected regions. The ASFV is spread through direct and indirect contact with infected pigs, their products and carrier vectors especially Ornithodoros ticks. Severe economic losses and a decline in pig production have been observed in ASFV affected countries, particularly in sub-Saharan Africa and Europe. At the end of 2018, the ASFV adversely affected China, the world's leading pork-producer. Control strategies for the disease remained challenging due to the unavailability of effective vaccines and the lack of successful therapeutic measures. However, considerable efforts have been made in recent years to understand the biology of the virus, surveillance and effective control measures. This review emphasizes and summarizes the current state of information regarding the knowledge of aetiology, epidemiology, transmission, and vaccine-based control measures against ASFV.

    Keywords: African Swine Fever Virus, pigs, Ticks, recombinant vaccines, Ornithodoros

    Received: 06 Apr 2024; Accepted: 19 Jun 2024.

    Copyright: © 2024 Alotaibi, Wu, Khan, Nawaz, Chen and Ali. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Abid Ali, Abdul Wali Khan University Mardan, Mardan, Pakistan

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.