This article is a correction to:
L-Ascorbic Acid Shapes Bovine Pasteurella multocida Serogroup A Infection
Guangfu Zhao
Pan Li
Hao Mu3†
Nengzhang Li
Yuanyi Peng- 1Chongqing Key Laboratory of Forage and Herbivorce, College of Veterinary Medicine, Southwest University, Chongqing, China
- 2Key Laboratory for Bio-Resource and Eco-Environment of Education of Ministry, The Center for Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, China
- 3Chongqing Academy of Animal Science, Chongqing, China
A corrigendum on
L-ascorbic acid shapes bovine Pasteurella multocida serogroup A infection
by Zhao, G., Li, P., Mu, H., Li, N., and Peng, Y. (2021). Front. Vet. Sci. 8:687922. doi: 10.3389/fvets.2021.687922
In the published article, there was an error in the legend for Figures 3A–D as published. The figure part labels were mixed up and the wrong description was given of each letter (A–D). The legend previously stated:
“(A) Analysis of some PmCQ2 virulence gene expression under different doses of AA. (B) Analysis of some PmCQ2 virulence gene expression under different doses of L-aspartic acid. Three repeats for each group. (C) PmCQ2 bioflim formation treated with different doses of AA or L-aspartic acid. Five repeats for each group. (D) The virulence gene, OmpA, expressions in the mice lung before infection or after 104 CFU log-phase growth PmCQ2 infection for 16 h. Three repeats for each group.”
The corrected legend appears below.
“(A) Analysis of some PmCQ2 virulence gene expression under different doses of L-aspartic acid. (B) Analysis of some PmCQ2 virulence gene expression under different doses of AA. Three repeats for each group. (C) The virulence gene, OmpA, expressions in the mice lung before infection or after 104 CFU log-phase growth PmCQ2 infection for 16 h. Three repeats for each group. (D) PmCQ2 biofilm formation treated with different doses of AA or L-aspartic acid. Five repeats for each group.”
In the published article, there was an error. The part labels for Figure 3 were mixed up and the wrong description was given of each letter (A-D).
A correction has been made to Results, AA Inhibits PmCQ2 Virulence Factor Expression and Bovine PmA Infection Leads to AA Deficiency, Paragraph 4. This sentence previously stated:
“As shown in Figure 3B, Asp showed no impact on the virulence gene expression, whereas AA downregulated two virulence genes, OmpA and oma87, in a dose-dependent manner (Figure 3A). Interestingly, in agreement with the metabolomics data, less AA was found in the infected lung than the liver with more OmpA expression (Figure 3D). In addition, it is found that AA significantly decreased PmCQ2 biofilm biogenesis while Asp promoted PmCQ2 biofilm biogenesis at low dosage (Figure 3C).”
The corrected sentence appears below:
“As shown in Figures 3A, B, Asp showed no impact on the virulence gene expression, whereas AA downregulated two virulence genes, OmpA and oma87, in a dose-dependent manner. Interestingly, in agreement with the metabolomics data, less AA was found in the infected lung than the liver with more OmpA expression (Figure 3C). In addition, it is found that AA significantly decreased PmCQ2 biofilm biogenesis while Asp promoted PmCQ2 biofilm biogenesis at low dosage (Figure 3D).”
A correction has been made to Discussion, Paragraph 3. This sentence previously stated:
“As shown in Figure 3C, bovine PmA biofilm formation is inhibited by AA, which is also consistent with published papers showing AA has a negative regulation on bacterial biofilm formation (Figure 3C) (43, 44). Consistent with previous results that infected lung owns less AA than the infected liver, higher OmpA expression was detected in the infected lung than the infected liver (Figure 3D).”
The corrected sentence appears below:
“As shown in Figure 3D, bovine PmA biofilm formation is inhibited by AA, which is also consistent with published papers showing AA has a negative regulation on bacterial biofilm formation (43, 44). Consistent with previous results that infected lung owns less AA than the infected liver, higher OmpA expression was detected in the infected lung than the infected liver (Figure 3C).”
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: Bovine Pasteurella multocida serogroup A, pneumonia, metabolomics, macrophage, L-ascorbic acid
Citation: Zhao G, Li P, Mu H, Li N and Peng Y (2023) Corrigendum: L-ascorbic acid shapes bovine Pasteurella multocida serogroup A infection. Front. Vet. Sci. 10:1281834. doi: 10.3389/fvets.2023.1281834
Received: 23 August 2023; Accepted: 31 August 2023;
Published: 12 September 2023.
Approved by:
Mujeeb Ur Rehman, Livestock and Dairy Development Department, PakistanCopyright © 2023 Zhao, Li, Mu, Li and Peng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Nengzhang Li, bGljaDIwMDEwMjAmI3gwMDA0MDsxNjMuY29t; Yuanyi Peng, cHl5MjAwMiYjeDAwMDQwO3NpbmEuY29t
†These authors have contributed equally to this work