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REVIEW article

Front. Lab. Chip. Technol.
Sec. Micro- and Nano-fabrication
Volume 3 - 2024 | doi: 10.3389/frlct.2024.1419570
This article is part of the Research Topic The Future of Lab on a Chip Technologies: An Early Career Scientists’ Perspective View all 6 articles

Electrochemical biosensors on microfluidic chips as promising tools to study microbial biofilms: a review

Provisionally accepted

The final, formatted version of the article will be published soon.

    Microbial biofilms play a pivotal role in microbial infections and antibiotic resistance due to their unique properties, driving the urgent need for advanced methodologies to study their behavior comprehensively across varied environmental contexts. While electrochemical biosensors have demonstrated success in understanding the dynamics of biofilms, scientists are now synergistically merging these biosensors with microfluidic technology. This combined approach offers heightened precision, sensitivity, and real-time monitoring capabilities, promising a more comprehensive understanding of biofilm behavior and its implications. Our review delves into recent advancements in electrochemical biosensors on microfluidic chips, specifically tailored for investigating biofilm dynamics, virulence, and properties. Through a critical examination of these advantages, properties and applications of these devices, the review highlights the transformative potential of this technology in advancing our understanding of microbial biofilms in different settings.

    Keywords: Microbial biofilms, electrochemical biosensors, Microfluidics, Real-time monitoring, Biofilm dynamics

    Received: 18 Apr 2024; Accepted: 14 Jun 2024.

    Copyright: © 2024 Abouhagger, Celiešiūtė-Germanienė, BAKUTE, Stirke and De Melo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wanessa De Cássia M. De Melo, Center For Physical Sciences And Technology (CPST), Vilnius, 02300, Lithuania

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.