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ORIGINAL RESEARCH article

Front. Public Health
Sec. Life-Course Epidemiology and Social Inequalities in Health
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1488294
This article is part of the Research Topic Insights and Advances in Surgical Best Practices for Gender Health Equity and Appropriateness View all 5 articles

Socioeconomic Status and Delayed Surgery: Impact on Non-Metastatic Papillary Thyroid Carcinoma Outcomes

Provisionally accepted
Kun Zhang Kun Zhang 1Xinyi Wang Xinyi Wang 1Jianyong Lei Jianyong Lei 1Anping Su Anping Su 1Tao Wei Tao Wei 1Zhihui Li Zhihui Li 1Ya-Wen Chen Ya-Wen Chen 2*
  • 1 West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
  • 2 Icahn School of Medicine at Mount Sinai, New York, United States

The final, formatted version of the article will be published soon.

    The growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment of the link between surgery delay and survival outcomes for papillary thyroid cancer. In this study, we aim to investigate the interplay among various oncological factors, socioeconomic status, and surgical timing with respect to survival outcomes of papillary thyroid cancer.Methods: A total of 58,378 non-metastatic papillary thyroid cancer patients from 2000 to 2018 were screened from the Surveillance, Epidemiology, and End Results database.Kaplan-Meier survival curve, Cox proportional hazard regression, competing risk hazard regression, and multinomial logistic regression were applied.Results: Receiving neck dissection or radioactive iodine therapy, being married at diagnosis, living in an urban area, being richer, and being of other minority ethnicity were estimated to be independent predictors for better overall survival. Single, older Black patients living in rural areas that experienced long surgery delays were more associated with a higher non-papillary thyroid cancer mortality rate. High income level was the only independent socioeconomic status predictor for lower papillary thyroid cancer -specific mortality. Unmarried, older patients of minority ethnicity tended to undergo longer surgery delays.Conclusions: Surgery for non-metastatic papillary thyroid cancer patients can be safely delayed. The elevated non-papillary thyroid cancer mortality has reflected low socioeconomic status population's survival status.

    Keywords: overall survival, prognostic factors, Papillary thyroid cancer, Socioeconomic status, surgery delay

    Received: 29 Aug 2024; Accepted: 30 Dec 2024.

    Copyright: © 2024 Zhang, Wang, Lei, Su, Wei, Li and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ya-Wen Chen, Icahn School of Medicine at Mount Sinai, New York, United States

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