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ORIGINAL RESEARCH article

Front. Psychiatry, 16 April 2021
Sec. Public Mental Health
This article is part of the Research Topic Excessive and Problematic Smartphone Usage View all 13 articles

Problematic Smartphone and Social Media Use Among Bangladeshi College and University Students Amid COVID-19: The Role of Psychological Well-Being and Pandemic Related Factors

\nMd. Saiful Islam,
Md. Saiful Islam1,2*Md. Safaet Hossain Sujan,Md. Safaet Hossain Sujan1,2Rafia Tasnim,Rafia Tasnim1,2Rashenda Aziz Mohona,Rashenda Aziz Mohona2,3Most. Zannatul FerdousMost. Zannatul Ferdous1Sk Kamruzzaman,Sk Kamruzzaman2,4Tanziha Yeasmin Toma,Tanziha Yeasmin Toma1,2Md. Nazmus Sakib,Md. Nazmus Sakib2,5Khairrun Nahar Pinky,Khairrun Nahar Pinky2,6Md. Riad Islam,Md. Riad Islam2,7Md. Abid Bin Siddique,Md. Abid Bin Siddique1,2Fahim Shariar Anter,Fahim Shariar Anter2,8Alomgir Hossain,Alomgir Hossain2,9Ikram Hossen,Ikram Hossen1,2Md. Tajuddin SikderMd. Tajuddin Sikder1Halley M. PontesHalley M. Pontes10
  • 1Department of Public Health and Informatics, Jahangirnagar University, Savar, Bangladesh
  • 2Centre for Advanced Research Excellence in Public Health, Dhaka, Bangladesh
  • 3Department of Public Health, North South University, Dhaka, Bangladesh
  • 4Faculty of Animal Science and Veterinary Medicine, Patuakhali Science and Technology University, Barishal, Bangladesh
  • 5Department of Ayurvedic Medicine, Hamdard University Bangladesh, Gazaria, Bangladesh
  • 6Department of Population Science and Human Resource Development, Rajshahi University, Rajshahi, Bangladesh
  • 7Department of Anthropology, Rajshahi University, Rajshahi, Bangladesh
  • 8Department of Biochemistry and Molecular Biology, Noakhali Science and Technology University, Noakhali, Bangladesh
  • 9Department of Genetic Engineering and Biotechnology, Rajshahi University, Rajshahi, Bangladesh
  • 10Department of Organizational Psychology, Birkbeck, University of London, London, United Kingdom

Background: Smartphone and social media use are an integral part of our daily life. Currently, the impact of excessive smartphone and social media use during the COVID-19 pandemic is poorly understood. The present study aimed to investigate problematic smartphone use (PSPU) and problematic social media use (PSMU) among Bangladeshi college and university students during the COVID-19 pandemic.

Methods: A cross-sectional study was carried out involving 5,511 Bangladeshi college and university students (male: 58.9%; mean age: 21.2 years [SD = 1.7]; age range: 18–25) during the social-distancing in the COVID-19 pandemic (July 2020). A self-reported survey containing questions regarding socio-demographic, lifestyle, and home quarantine activities along with four psychometric scales was completed by participants.

Results: The mean scores of PSPU and PSMU were 20.8 ± 6.8 (out of 36) and 14.7 ± 4.8 (out of 30). Based on a hierarchical regression analysis, PSPU and PSMU were positively associated with lower age, poor sleep, social media use, watching television, anxiety, and depression. Additionally, PSMU was linked to being female, living with nuclear family, having urban residence, irregular physical exercise, poor engagement with academic studies, and avoiding earning activities, whilst being male, being married, living with lower-income family, and alcohol consumption were linked to PSMU.

Conclusions: The findings indicate that PSPU and PSMU were linked to poor psychological well-being (i.e., anxiety and depression) and other factors (especially lower age, poor sleep) during the pandemic, further suggesting the need for interventions including virtual awareness programs among college and university students.

Introduction

Currently, the world is facing a public health emergency declared by the World Health Organization due to international concerns regarding the highly contagious nature of COVID-19 (1). In Bangladesh (where the present study was carried out), the first three cases of COVID-19 were identified on March 8th 2020 (2, 3). Since then, the virus has continued to spread swiftly, and resulted in 430,496 positive cases with 6,173 fatalities by November 14th, 2020 (4, 5). As an immediate response to control the rapid spread of COVID-19, the Bangladesh government declared a “lock-down” or “stay at home order” on March 26, 2020 (6, 7). Everything including transports, shopping malls, offices, industries, and educational institutions got closed (8) and therefore, the government encouraged individuals to carry study, shopping, and work online at home. The initial restrictions (i.e., lock-down and social-distancing) aimed at controlling the spread of COVID-19 may have led to negative psychological impacts (e.g., anxiety, depression, frustration, fear, stress) to many individuals (9, 10). To help to cope with these negative mood states, individuals may engage in psychoactive substance use or engage problematically in specific technology use behaviors such as smartphone use, social media use, and video gaming as these potentially addictive behaviors may help alleviate the burden of stress and difficult thoughts experienced by individuals (11). However, the use of social media grew exponentially in the context of the COVID-19 pandemic (12). Higher amounts of time spent using social media may be problematic as these online platforms can be addictive (13). Social media platforms promote constant scrolling and do not have a definite “stop point,” which is why they can lead to individuals spending several hours using these online platforms (14). The use of social media is widespread amongst adolescents attending college and university (1517). Recently, adolescents' smartphone use has been reported to constitute a potentially problematic issue (18, 19) due to the rise in smartphone use and its increased popularity through applications such as social media, gaming, streaming, and education to individuals with low levels of health literacy.

As shown by previous research, dysregulated use of smartphone is associated with sleep disturbance, and depressive symptoms among adolescents (20). The use of social media in classroom for educational purposes is becoming increasingly popular, with educators massively adopting it during the social-isolation period because of its enhanced communication potential, content distribution, collaborations, and engagement with the students (12). Furthermore, a recent study found that internet-based smartphone use can increase perceived quality of life by providing positive connections on social media, online shopping, online conferencing, and constant interaction with friends and family living in different countries (21).

Psychological health issues such as depression and anxiety have been positively linked with problematic smartphone use (PSPU) (22). Moreover, the COVID-19 pandemic and subsequent home quarantine and social-distancing requirements, have increased anxiety levels, and the extent of negative emotions experienced across society (23, 24), and through easily available means, many individuals seek emotional comfort by using smartphones and the internet as potential coping mechanisms. However, the adoption of such coping mechanisms may lead to many potential negative consequences because of functional impairments due to excessive usage (25, 26). PSPU has been characterized as severe levels of dysregulated smartphone use leading to problems in areas such as social, professional, and/or academic, with symptoms arguably similar to substance use disorders [e.g., withdrawal use, tolerance, careless use; (27)].

Bangladesh (where the present study was carried out) is a developing nation that is trying to become increasingly digitalized by enhancing internet use within the population, thus potentially increasing the extent of excessive usage of digital devices and the internet. At the end of January 2020, the total number of internet users in the country was over 99 million (28), and with this figure gradually increasing. Moreover, most of the country's internet users have smartphones. It is likely that, the required social-distancing measures may exacerbate excessive usage of smartphones and social media websites, especially among youth (29, 30).

To date, there are no previous studies focusing on PSPU and problematic social media use (PSMU) among college and university students in Bangladeshi in the context of the COVID-19 pandemic. Therefore, the present study aims to investigate the correlates of PSPU and PSMU with psychological well-being, socio-demographics, lifestyle, and home quarantine regular/frequent activities among college and university students in Bangladeshi during the COVID-19 pandemic. The study will inform future similar research and the development of new policies aiming to ascertain how Bangladeshi college and university students might be affected smartphone and social media use during the COVID-19 pandemic.

Materials and Methods

Participants and Procedure

The present cross-sectional study was conducted among Bangladeshi college and university students during the social-distancing period in the context of the COVID-19 pandemic. Data collection took place during in July 2020 using an online self-reported survey. All questions related to the survey were administered using Google Forms and a shareable link was generated to help disseminate the survey across different online platforms used by college and university students. The online survey detailed the study's informed consent, purpose, inclusion, and exclusion criteria on the first page. The inclusion criteria included (i) being 18 years old and above, (ii) being a Bangladeshi college or university student, (iii) owning a smartphone and having access to the internet, and (iv) being surveyed voluntarily. The exclusion criteria were (i) being under 18 years and (ii) not being completing the online survey entirely.

Measures

A self-reported and structured online survey containing questions regarding participants' socio-demographic, lifestyle, and home quarantine activities along with four psychometric tests to measure the variables of the study were employed to collect data.

Socio-Demographic and Lifestyle Measures

Socio-demographic information concerning gender, age, marital status, education level, family type, and residence (urban/rural) was collected from all participants. Socio-economic status (SES) was categorized into three classes according to previous literature: lower, middle, and upper based on monthly family income of <15,000 Bangladeshi Taka (BDT) ≈ 177 US$, 15,000–30,000 BDT ≈ 177–354 US$, and more than 30,000 BDT ≈354 US$, respectively (31, 32). Moreover, numbers of average sleep hours classed as normal [7–9 h], less than normal [<7 h], or more than normal [>9 h] based on previous literature (3335), physical exercising (yes/no), smoking cigarettes, and alcohol consumption (yes/no) were collected with regard to lifestyle measures.

Home Quarantine Activities Measures During COVID-19

Additional dichotomous questions (yes/no) were asked regarding the engagement in frequent activities during the pandemic, including home quarantine regular/frequent activities (i.e., academic/other studies, social-media use, watching television, household chores, and professional activities).

Patient Health Questionnaire (PHQ-9)

The PHQ−9 is a nine-item scale that measures depressive symptoms in the last 2 weeks (36). The items are rated from 0 (Not at all) to 3 (Nearly every day). Total scores can be obtained by summing up all responses on each item, and they range from 0 to 27. The present study used the Bangla version PHQ-9 (37) to assess participants' depressive symptoms as in previous research (3840). The cutoff score ≥10 was used as a potential indication of depression in the sample recruited as previously in Bangladesh (32, 38, 41). In the present study, the PHQ-9 scale presented excellent internal consistency (Cronbach's alpha = 0.89).

Generalized Anxiety Disorder (GAD-7)

The GAD-7 is commonly used to screen symptoms and severity of generalized anxiety in epidemiological research (42). This scale consists of seven items that can be responded to on a four-point Likert scale ranging from 0 (Not at all) to 3 (Nearly every day). The present study adopted the Bangla version of the GAD-7 to assess participants' levels of anxiety as in previous research (39, 43, 44). The cutoff score ≥10 was used as indicative of anxiety as previously done in Bangladesh (39, 43). In the present study, the GAD-7 scale was observed as excellent reliability (Cronbach's alpha = 0.91).

Bergen Social Media Addiction Scale (BSMAS)

The BSMAS assesses PSMU with six questions based on the components model of addiction (i.e., salience, mood, modification, tolerance, withdrawal conflict, and relapse) proposed by Griffiths (49). The BSMAS was developed by Andreassen et al. (45), and was used to assess social media addiction by symptoms and related negative outcomes due to problematic use over the past year (e.g., “How often during the last week have spent a lot of time thinking about social media or planned use of social media?”). All items of the BSMAS can be responded using a five-point Likert scale ranging from 1 (very rarely) to 5 (very often). The total score is yielded by summating each items' raw score, with higher scores suggesting greater levels of PSMU symptoms. In the present study, the translated Bangla version of BSMAS was used to investigate PSMU. The BSMAS used in the study was adapted using a “back translation” procedure [i.e., (46)], similar to previous research conducted in Bangladesh (7, 47). In the present study, the Cronbach's alpha of BSMAS was 0.80.

Smartphone Application Based Addiction Scale (SABAS)

The SABAS was developed by Csibi et al. (48) and it consists of six items that measure PSPU. The scale was used to determine the extent of PSPU. The SABAS was developed based on the components model of addiction (i.e., salience, alteration of the mood, tolerance, withdrawal conflict, and relapse) which was proposed by Griffiths (49). Sample items include: “During the past week, my smartphone is the most important thing in my life.” All items are rated on a six-point Likert scale ranging from 1 (strongly disagree) to 6 (strongly agree). Total scores are summed up to reflect participants' overall levels of PSPU, with elevated scores suggesting a higher degree of PSPU. In the present study, the Bangla version of the SABAS was translated using a “back translation” procedure [i.e., (46)], similar to previous studies in Bangladesh (7, 47). In the present study, the Cronbach's alpha of the SABAS was 0.85.

Statistical Analysis

Data were analyzed using Microsoft Excel 2019 and SPSS version 25. Firstly, the data set was cleaned, sorted, and coded using Microsoft Excel and exported onto SPSS. Using SPSS, descriptive statistics (i.e., frequencies, percentages, means, standard deviation estimates) were computed. Inferential statistics included conducting t-tests or one-way Analysis of Variance (ANOVA) to determine mean differences in the scores of the SABAS and BSMAS in relation to all variables examined applying Bonferroni correction (via dividing p-value significance threshold [0.05] into the number of independent variables: 0.05/18 = 0.003). Finally, multiple linear regression analyses predicting PSPU and PSMU across two independent models were conducted using a hierarchical approach including four blocks of predictors pertaining to: socio-demographic, lifestyle, home quarantine regular/frequent activities, and psychological well-being factors.

Ethics

All procedures of the present study were performed in compliance with the Declaration of Helsinki, and adopting with guidelines of institutional research ethics. The present study has obtained ethical approval, which was given by the Ethical Review Committee (Ref. no: UAMC/ERC/17/2020). After being informed about the study's aims and procedures, all participants consented to participate in the study. Participants' information was strictly kept anonymous and confidential.

Results

Participants' Socio-Demographic Features

A total of 5,511 participants were included in the final analysis (see Table 1). Of these, 58.9% were male participants. The sample's average age was 21.2 years (SD = 1.7 years) and ages ranged from 18 to 25 years. The sample comprised college (22.9%) and university (77.1%) students. In terms of marital status, most participants were unmarried (95.8%). The majority of participants lived with their nuclear families (78.3%), held middle-class socioeconomic status (42.8%), and were from urban areas (50.5%). A sizeable minority did not engage in regular exercising (41.5%), and the majority were classed as normal sleepers (7–9 h/day) (67.6%). Last but not least, about 11.1% of all participants reported smoking cigarettes while a minority reported consuming alcohol (3.2%).

TABLE 1
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Table 1. Descriptive analyses of all examined variables (N = 5,511).

Associations Between PSPU and PSMU With Other Variables

The mean score of PSPU was 20.8 (SD = 6.8) out of 36. Moreover, high PSPU scores were positively associated with lower age, being female, being a university student, living in a nuclear family, being from an upper-class family, having urban residence, exhibiting poor physical exercising habits, greater sleep, smoking cigarettes, not consuming alcohol, not engaging with study, using social media, watching television shows, avoiding household chores, not in engaging earning activities, high levels of anxiety, and depression (Table 2).

TABLE 2
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Table 2. Associations between Problematic Smartphone Use (PSPU) and Problematic Social Media Use (PSMU) with all variables examined (N = 5,511).

The mean score of PSMU was 14.7 (SD = 4.8) out of 30. Similarly, high PSMU scores were positively associated with lower age, being female, being a college student, living in a nuclear family, being from a lower-class family, having urban residence, exhibiting poor physical exercising habits, less/more sleep, smoking cigarettes, alcohol consumption, not engaging with study, using social media, watching television, avoiding household chores, not engaging earning activities, high levels of anxiety, and depression (Table 2). Finally, a statistically significant positive correlation emerged between PSPU and PSMU (r = 0.61, p < 0.001).

Factors Affecting PSPU and PSMU

The results of the hierarchical regression analysis predicting PSPU are presented in Table 3. Factors that were statistically significant in the group difference analyses (t-tests and ANOVA) were included in a hierarchical regression analysis. Socio-demographic factors (i.e., age, gender, educational level, family type, monthly family income, and residence) were included in Block 1. Lifestyle factors (i.e., physical exercise, sleeping hours, smoking cigarettes, and alcohol consumption) comprised Block 2. In Block 3, home quarantine activities (i.e., study, social media use, watching television, household chores, and earning activities) were included, while Block 4 comprised psychological well-being factors (i.e., anxiety and depression).

TABLE 3
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Table 3. Hierarchical regression analysis predicting Problematic Smartphone Use (PSPU).

Overall, the regression model (Model 4) estimated predicted about 30% of the total variance in PSPU [F(17, 5, 493)= 139.12, p < 0.001]. In terms of specific predictors (applying Bonferroni correction), PSPU was predicted by irregular physical exercise, poor engagement with academic studies, social media use, watching television, avoiding earning activities, high levels of anxiety and depression. Consequently, age, gender, educational level, family type, monthly family income, residence, sleeping hours, smoking cigarettes, alcohol consumption, and household chores were not statistically significant predictors in the hierarchical regression analysis.

In relation to PSMU, the results of the hierarchical regression analysis indicated that the regression model (Model 4) predicted about 25% of the total variance in PSMU [F(17, 5, 493)= 110.44, p < 0.001; see Table 4]. Factors that were statistically significant in the group difference analyses (t-tests and ANOVA) were included in a hierarchical regression analysis. Socio-demographic factors (i.e., age, gender, educational level, family type, monthly family income, and residence) were included in Block 1. Lifestyle factors (i.e., physical exercise, sleeping hours, smoking cigarettes, and alcohol consumption) comprised Block 2. In Block 3, home quarantine activities (i.e., study, social media use, watching television, household chores, and earning activities) were included, and Block 4 comprised psychological well-being factors (i.e., anxiety and depression). Accordingly, PSMU was predicted (applying Bonferroni correction) by younger age, poor sleep (<7 h/day), alcohol consumption, social media use, high levels of anxiety, and depression. Consequently, gender, educational level, family type, monthly family income, residence, physical exercise, smoking cigarettes, study, watching television, household chores, and earning activities were not statistically significant predictors in the hierarchical regression analysis.

TABLE 4
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Table 4. Hierarchical regression analysis predicting Problematic Social Media Use (PSMU).

Discussion

Since the beginning of the COVID-19 pandemic, the use of smartphone and social media has rapidly increased globally, with digital technology use being associated with poorer mental health (50). Throughout modern societies, smartphone use became pervasive and can be seen across the entire lifespan. Moreover, social media and smartphone use has become essential in daily life as it provides access to a wide range of mobile applications, information, communication, education, and entertainment tools. The use of smartphones and the internet are a cause for concern for various communities due to the deleterious effects stemming from problematic use (51, 52).

To the best of the authors' knowledge, this is the first study investigating the intricacies between PSPU and PSMU in relation to key associated factors during the COVID-19 pandemic in Bangladesh. According to the findings obtained in this study, PSMU was positively associated with irregular physical exercise, poor engagement with academic studies, social media use, watching television, ignoring earning activities, anxiety, and depression. Similarly, PSMU was positively associated with lower age, poor sleep, alcohol consumption, social media use, anxiety, and depression. Moreover, according to the hierarchical regression analyses conducted, individuals with irregular physical activity were found to exhibit higher levels of PSPU than physically active individuals, a finding that corroborates the results of previous research conducted in Korea (53) and Switzerland (54) reporting that problematic users were less willing to exercise regularly.

The present study found that PSPU was significantly associated with poor study engagement. Previous studies reported that PSPU has an adverse effect on academic performance (55, 56). This finding is aligned with existing evidence indicating that prolonged smartphone use in adolescents is linked with poorer academic performance (52). Additionally, students at high risk of PSPU are less likely to have high grade point averages (GPAs) (57). Furthermore, PSPU was higher among social media users, which is consistent with previous research indicating that PSMU can occur among smartphone users (58).

Using smartphone as a source of entertainment (e.g., social media), has been found to be linked with PSPU according to an earlier study (59). Furthermore, participants using social media through their smartphones have been found to spend 0.5–3 h daily using social media (60), with greater time spent using social media posing greater addictive risk, and potentially contributing to greater PSPU risk (58). Moreover, the results of this study found that depression, and anxiety were positively associated with PSPU, which is consistent with several preceding studies showing a significant association between PSPU and both depression and anxiety symptoms (59, 61, 62). According to the findings obtained in this study, lower age was found to be positively associated with PSMU, which is similar to an earlier study (63). During home quarantine and self-isolation period, the main way to meet new people and socialize was through social media platforms, which potentially contributing to greater time spent on social media sites in order to alleviate the venerable psychological sates brought about by the pandemic (64, 65). Social media in today's society is widespread and, with excessive usage potentially leading to PSMU, particularly young people. Although social media may be used to communicate and establish connections with friends and significant others, excessive use can occur, leading to the development of PSMU (66).

In the hierarchical regression analysis conducted, reporting with less sleep (<7 h/day) were more prone to PSMU. An earlier study in the same country also supports this finding (67). Research has shown that both inadequate and prolonged sleep (68) are associated with PSMU. Another important finding was that alcohol consumption and PSMU were positively associated in the present study. Participants consuming alcohol may become more engaged in alcohol-related social media usage (69), spending more time using social media, which may lead to excessive use. Depression and anxiety were also positively associated with PSMU according to the findings of obtained. Several preceding studies have found an association between both depression and anxiety with PSMU (61, 67, 7072), with longitudinal research showing a strong association between depression and trend of internet use (73).

The present study investigated potential factors associated with PSPU and PSMU during the COVID-19 pandemic. We have examined several factors (i.e., psychological well-being, socio-demographics, lifestyle, and home quarantine activities) predicting PSPU and PSMU during home quarantine in the context of the COVID-19 pandemic. Further evaluation is needed after the pandemic in order to estimate the potential psychiatric toll in terms of post-traumatic stress disorder symptoms among both excessive and problematic digital technology users.

Limitations

The present study is not without potential limitations. Firstly, causality cannot be established based on the findings reported due to the cross-sectional design adopted. As we did not have pre-COVID-19 data, the findings obtained cannot be causally inferred in that the COVID-19 pandemic leads to PSPU and PSMU. In this context, longitudinal and experimental studies will assist in exploring causal factors leading to PSPU and PSMU. Secondly, this study employed a self-report approach, which is likely to introduce specific biases (e.g., social desirability and memory recall biases). Furthermore, this study was conducted on a convenience sample of college and university students from Bangladesh, which cannot be representative of other populations and users around the globe. So, a longitudinal study focusing on different groups is needed.

Conclusions

The present study focused on the factors associated with PSPU and PSMU during the COVID-19 pandemic. It can therefore be concluded that the COVID-19 pandemic led to an innovative utilization of smartphone and social media that helped keeping the population informed and socially connected during the COVID-19 pandemic, but excessive use may become an issue, leading to problematic usage. Psychosocial education and counseling programs should be implemented to prevent and mitigate the development of PSPU and PSMU and related psychological problems especially among vulnerable populations.

Data Availability Statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

Ethics Statement

The studies involving human participants were reviewed and approved by the Ethical Review Committee, Uttara Adhunik Medical College, Uttara, Dhaka-1260, Bangladesh (Ref. no: UAMC/ERC/17/2020). The patients/participants provided their written informed consent to participate in this study.

Author Contributions

MSI, MSuj, RT, and MF: conceptualization. MSI, MSuj, and MF: methodology. MSI: formal analysis and investigation. MSI, MSuj, RT, and RM: writing—original draft preparation. MSI, MF, MSik, and HP: writing—review and editing. SK, TT, MSak, KP, MRI, MSid, FA, AH, and IH: resources. MF and MSik: supervision. All authors read and approved the final manuscript.

Conflict of Interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Acknowledgments

Firstly, the authors would like to express the most profound gratitude to all of the participants who participated in this study voluntarily and spontaneously. Secondly, the authors would like to express the heartiest gratitude to all volunteers for their significant contributions during the data collection period by sharing the survey link in various online platforms (see responsible individuals in Supplementary Materials).

Supplementary Material

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpsyt.2021.647386/full#supplementary-material

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Keywords: problematic use, smartphone, social media, college, university, students, Bangladesh

Citation: Islam MS, Sujan MSH, Tasnim R, Mohona RA, Ferdous MZ, Kamruzzaman S, Toma TY, Sakib MN, Pinky KN, Islam MR, Siddique MAB, Anter FS, Hossain A, Hossen I, Sikder MT and Pontes HM (2021) Problematic Smartphone and Social Media Use Among Bangladeshi College and University Students Amid COVID-19: The Role of Psychological Well-Being and Pandemic Related Factors. Front. Psychiatry 12:647386. doi: 10.3389/fpsyt.2021.647386

Received: 04 January 2021; Accepted: 05 March 2021;
Published: 16 April 2021.

Edited by:

Chung-Ying Lin, National Cheng Kung University, Taiwan

Reviewed by:

Meng-Che Tsai, National Cheng Kung University Hospital, Taiwan
Yun-Hsuan Chang, Asia University, Taiwan

Copyright © 2021 Islam, Sujan, Tasnim, Mohona, Ferdous, Kamruzzaman, Toma, Sakib, Pinky, Islam, Siddique, Anter, Hossain, Hossen, Sikder and Pontes. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Md. Saiful Islam, c2FpZnVsJiN4MDAwNDA7cGhpanUuZWR1LmJk; aXNsYW0ubXNhaWZ1bCYjeDAwMDQwO291dGxvb2suY29t

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