Skip to main content

SYSTEMATIC REVIEW article

Front. Psychiatry, 21 September 2018
Sec. Public Mental Health
This article is part of the Research Topic Refugee Mental Health View all 15 articles

Psychiatric Disorders in Refugees and Internally Displaced Persons After Forced Displacement: A Systematic Review

  • 1Department of Consultation Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland
  • 2School of Psychology, University of New South Wales, Sydney, NSW, Australia
  • 3Institute for Complementary and Integrative Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland

Background: Protracted armed conflicts not only shape political, legal, and socio-economic structures, but also have a lasting impact on people's human migration. In 2017, the United Nations High Commissioner for Refugees reported an unprecedented number of 65.6 million individuals who were displaced worldwide as a result of armed conflicts. To date, however, little is known about these people's mental health status. Therefore, we conducted a systematic review of the prevalence of psychiatric disorders among forcibly displaced populations in settings of armed conflicts.

Methods: We undertook a database search using Medline, PsycINFO, PILOTS, and the Cochrane Library, using the following keywords and their appropriate synonyms to identify relevant articles for possible inclusion: “mental health,” “refugees,” “internally displaced people,” “survey,” and “war.” This search was limited to original articles, systematic reviews, and meta-analyses published after 1980. We reviewed studies with prevalence rates of common psychiatric disorders—mood and anxiety disorders, psychotic disorders, personality disorders, substance abuse, and suicidality—among adult internally displaced persons (IDPs) and refugees afflicted by armed conflicts.

Results: The search initially yielded 915 articles. Of these references 38 studies were eligible and provided data for a total of 39,518 adult IDPs and refugees from 21 countries. The highest prevalence were for reported for post-traumatic stress disorder (3–88%), depression (5–80%), and anxiety disorders (1–81%) with large variation. Only 12 original articles reported about other mental disorders.

Conclusions: These results show a substantial lack of data concerning the wider extent of psychiatric disability among people living in protracted displacement situations. Ambitious assessment programs are needed to support the implementation of sustainable global mental health policies in war-torn countries. Finally, there is an urgent need for large-scale interventions that address psychiatric disorders in refugees and internally displaced persons after displacement.

Introduction

“War should be understood as an actual, intentional, and widespread armed conflict between political communities […], defined as those entities which either are states or intend to become states […]” (1). Whether considered from a philosophical, sociological, or legal perspective, war remains one of the most complex and devastating human enterprises (1). In 2016, according to the Department of Peace and Conflict Research at the University of Uppsala, 51 ongoing armed conflicts were reported worldwide and well over 100,000 people were killed in organized violence (2). Beyond this sole number, the entire ecology of war has dramatically changed over the past two decades. Altogether less frequent, armed conflicts have reached low- and middle-income countries (LMICs) more frequently and become predominantly intrastate and disproportionately protracted in nature (3).

Intrastate, irregular, and protracted armed conflicts have drastically influenced recent figures of global displacement (4). In its 2017 Global Trends Report, the United Nations High Commissioner for Refugees (UNHCR) announced an estimated 10.3 million newly displaced individuals—Syria being the most affected country—and an overall number of 65.6 million forcibly displaced people worldwide (5). While UNHCR refugee statistics have demonstrated a substantial stabilization of the number of out-of-country refugees over the past 10 years, numbers of internally displaced people (IDP) have reached unparalleled levels representing more than 65% of the displaced population globally (6). In 2016 alone, conflict and violence gave rise to 6.9 million new IDPs, which disproportionately came from LMICs.

Organized violence has profound and catastrophic structural effects on already fragile developing countries, where 84% of the world's refugees live (5); political and economic structures are undermined, laws are overstepped, fundamental rights of individuals are often abused, and healthcare services shattered (3, 7, 8). Quantifying the magnitude of these consequences on people undoubtedly remains an intricate challenge (7). However, numerous public health studies in complex humanitarian settings have shown that armed conflicts critically affect mental health (6, 911).

Reliable assessments of mental health needs in humanitarian settings should be viewed as a public health priority. In fact, no mental health policies can be efficiently implemented without an accurate assessment. This seems particularly true today: numbers of global displacement related to conflicts are increasing dramatically, common camp-based models of displaced populations are becoming outdated—60% of IDPs are currently living in urban areas without any international protection—and the heavy burden of psychiatric diseases in LMICs are being acknowledged (3, 12).

Based on the assumption that conflict-affected populations will be traumatized, most studies have singularly focused on PTSD whilst largely ignoring other psychiatric disorders. Considering psychological trauma or depression as main research objectives in settings of generalized violence or unresolved conflicts is a major intellectual misapprehension. It fails to appreciate the extent of global repercussions on mental health, that is, the risks of intense psychological distress in otherwise healthy individuals and increased neuropsychiatric diseases or the worsening of chronic mental illnesses due to an aggravated lack of medical resources (1315). Additionally, these risks interact with several environmental factors that directly influence mental health such as forced evacuation of homes and separation from family members, interpersonal tensions, or loss of employment opportunities (1315).

Two previous systematic reviews have evaluated prevalence rates of psychiatric disorders in refugee populations. Steel et al. (16) conducted a systematic review and meta-analysis finding higher prevalence rates of PTSD and depression in conflict-displaced refugees globally. Another review from Ezard et al. (17) observed the rates of substance abuse among refugees displaced by conflict and reported on associated risk factors and outcomes. There is still a paucity of data on the epidemiology of mental illness in populations displaced by armed conflicts. This is especially true for less common psychiatric disorders such as psychotic disorders. Therefore, we conducted a systematic review to summarize the prevalence of common psychiatric disorders, as well as more severe—uncommon—psychiatric disorders in IDPs and refugees still residing in LMIC's. We also report on the methods of assessing mental illness, number, and types of traumatic events, and the duration of the displacement experience.

Methods

To ensure the highest standardized methods of reviewing process, the conduct of this research was guided by the PRISMA guidelines for systematic reviews and meta-analyses (18).

Search Strategy

We undertook a sequential database search using MEDLINE via PubMed, PsycINFO, PILOTS, and the Cochrane library of systematic reviews. Medical Subject Headings with related text-based search terms were used with a combination of the following terms and concepts: “mental health,” “refugees,” “prevalence,” and “war.” In addition, articles indexed by “internally displaced people” were identified using the method of single keywords. Similarly, in the PILOTS database, an online index collecting the literature on PTSD and mental health consequences of traumatic events (19), a combination of single keywords and their synonyms was used to identify pertinent studies: “mental health,”refugees,”internally displaced people,”war,”prevalence,” and “humanitarian settings.” Relevant gray literature (unpublished articles, international reports, or non-governmental epidemiological surveys) was retrieved through an internet search. Lastly, citations from relevant articles and systematic reviews were also screened. This initial process yielded an overall number of 915 articles: 902 were generated through systematized database search, while 13 were retrieved from the gray literature and article/systematic review bibliographies (Figure 1).

FIGURE 1
www.frontiersin.org

Figure 1. Research strategy to identify eligible articles examining common mental disorders among IDPs and people in protracted refugee situations. AS, Asylum Seekers; CMD, Common Mental Disorders; En/Fr/Ger, English/French/German; HIC, High Income Countries; MH, Mental Health; MHP, Mental Health Programs; RF, Refugees; WWII, World War II.

Inclusion and Exclusion Criteria

Studies were considered eligible for the review if they assessed the prevalence of common mental disorders among internally displaced people and refugees afflicted by armed conflicts in a war region or unstable country. Original articles written in English, French, and German were included. The issue of internally displaced or refugee children and adolescents should be addressed separately (2023) and therefore, an age limit of ≥16 was selected as an inclusion criterion. We also limited our research to articles published after 1980 as interests about global mental health in war-torn countries emerged after 1980 when mental health progressively became an integral part of the field of public health (24). The status of conflict and displacement were other important inclusion criteria. We only included studies that reported results from or were completed in countries where conflicts were unresolved at the time of investigation and if study samples consisted of populations in protracted displacement situations. However, the UNHCR definition of “protracted refugee situations”— ≥ 25,000 people gathered outside of their country of residence for ≥5 consecutive years—was not considered as part of the selection process (25). In this context, we did not restrict article selection according to the numbers of IDPs or refugees and years of displacement, since many authors did not report this information. Furthermore, we only included studies from LMICs defined according to the Gross National Income per capita classification proposed by the World Bank (26). We did so for two principal reasons. On the one hand, mental disorders among resettled refugees in Western high-income countries (HIC) have been investigated to a great extent in the light of PTSD, depression, and anxiety disorders (27). On the other hand, contextual factors such as a lower likelihood of being exposed to an ongoing conflict and its myriad consequences, resettlement in stable accommodations, greater economic or educational opportunities uniquely distinguish resettled refugees in HIC from displaced populations in LMICs (28). Finally, case reports, qualitative studies, systematic reviews, meta-analyses, and articles reporting consequences of natural disasters on mental health were excluded.

In order to precisely define the term refugee, the 1951 Refugee Convention was considered (29, 30): a refugee is a person who has crossed the international borders of his or her country of origin due to a “well-founded fear of being persecuted for reasons of race, religion, nationality, membership of a particular social group or political opinion,” and “is unable to, or owing to such fear, is unwilling to avail himself of the protection of that country.” Related to this, internally displaced people are “persons or groups of persons who have been forced or obliged to flee […] their homes […], in particular as a result or in order to avoid the effects of armed conflict, situations of generalized violence, violations of human rights […] or human-made disasters, and who have not crossed an internationally recognized state border” (12).

Study Selection and Data Extraction

Study selection and data extraction were completed independently by two reviewers (LL & AA) in duplicate; disagreements between them were resolved by a third reviewer (NM). The following study characteristics were extracted: type and year of study, regionality, sample size, sampling method (when available), and type of assessment method of psychiatric disorders. With regard to assessment, different potential situations were examined: clinical diagnosis provided by a mental health care specialist according to the Diagnostic and Statistical Manual of Mental Disorders [DSM; (31)] or the International Classification of Disease [ICD; (32)], clinical assessment provided by a trained interviewer using various methods such as the Harvard Trauma Questionnaire [HTQ; (33)], or the Hopkins Symptom Checklist-25 [HSCL-25; (34)], and mental health evaluation by means of a self-administered questionnaire. We extracted prevalence rates of mental disorders but scores of scales were not used. More importantly, we did not restrict the extraction to disorders such as PTSD, depression, or anxiety disorders but included also general neuropsychiatric illnesses and, when applicable, general distress. Additional data extracted covered: type, year, and country of conflict (the total duration of conflict was inferred); status, country, and length of displacement; average number of experienced and/or witnessed traumatic events; mean age of study participants, and male to female ratio. In order to compare countries in terms of severity of conflicts, levels of generalized violence, and political instability, we introduced the Political Terror Scale [PTS; (35)], an 5-level score developed by the American non-governmental organization (NGO) Freedom House in the early 1980s. This score uses data provided by Amnesty International and the U.S. Department of State. Countries with a PTS score equal to 1 are legally and politically stable, whereas countries with PTS scores equal to or greater than 4 are notably characterized by extensive human rights violations and increasing levels of politically and ideologically motivated violence.

Results

We investigated 38 eligible original studies (Table 1) reporting data from a total population of 39,158 adult IDPs and refugees.

TABLE 1
www.frontiersin.org

Table 1. Detailed analysis of studies meeting inclusion criteria (N = 38).

Origin of Studies

Conflict-affected regions and host countries of displaced populations were unevenly represented: six original studies were conducted in the Middle East (Iran, Syria, Jordan, Lebanon, and Turkey) (44, 59, 67, 68, 70, 71), two were conducted in Latin America (Mexico, Colombia) (10, 55), six in Central and Eastern Europe (Croatia and Georgia) (38, 40, 6163, 66), eight in Asia (Thailand, Myanmar, Sri Lanka, Nepal, China, and Cambodia) (36, 37, 41, 43, 45, 48, 54, 60), and 16 in Africa (Sudan, Uganda, Liberia, Nigeria, Kenya, The Gambia, Senegal, and Ethiopia) (11, 39, 42, 46, 47, 4953, 5658, 64, 65, 69). The majority of studies were conducted in countries with a PTS score of 4 (n = 13) or 5 (n = 18).

Demographics

With regard to demographic factors, 26 studies (10, 11, 36, 3841, 45, 47, 50, 51, 5456, 5866, 6971) reported on samples that consisted of a majority (50–75%) of internally displaced or refugee women. Mean age ranged between 30 and 40 years in 21 studies (10, 11, 36, 38, 39, 42, 43, 46, 47, 4952, 58, 60, 6365, 68, 69, 71). In terms of status of displacement, our systematic research yielded quasi-similar results: IDPs and refugees were the primary population of interest in 16 countries (11, 4851, 5356, 58, 6065) and 16 studies (10, 11, 36, 38, 40, 42, 43, 4547, 52, 57, 59, 66, 67, 69), respectively. The mean duration of displacement ranged from 6 months to 18 years (10, 36, 38, 42, 43, 45, 4759). Although the strict UNHCR concept of protracted situation was not used as an inclusion criterion, nine studies selected in this review described durations of displacement >5 years (10, 36, 4345, 51, 5658). Levels of traumatic exposure among forcibly displaced populations were significant and reached an average number of seven experienced and/or witnessed traumatic events per participant (10, 11, 37, 38, 40, 42, 48, 5052, 54, 56, 61, 65, 69). These events included different forms of psychological stressors: witnessing the murder of a family member, friend, or stranger; being close to death, tortured, beaten, or arbitrarily imprisoned; being violently separated from family or isolated from other social groups, raped or sexually abused, and forced to accept ideas against one's will (11, 46).

Assessment Methods

Most eligible studies included in our review used well-established mental health questionnaires administered by trained lay interviewers or medical practitioners. Questionnaires were systematically assessed for cultural validity, translated, and administered in the participants' native language. The HTQ (33) was the preferred assessment method and was used in almost 50% of the studies looking into the prevalence of PTSD [15 of 33 studies; (10, 11, 3642, 48, 51, 54, 65, 66)]. Anxiety disorders and depression were mostly assessed through the HSCL-25 [17 of 31 studies; (34)] (10, 11, 3639, 41, 42, 45, 48, 5052, 54, 59, 66). With regard to PTSD, depression, and anxiety disorders, several authors also reported the Composite International Diagnostic Interview [CIDI; (72)] as a cross-culturally validated assessment method consisting of structured clinical interviews based on DSM-IV and ICD-10 diagnostic criteria (43, 48, 52, 60, 65). In two distinct studies, clinicians administered specific CIDI modules in order to validate the diagnoses mentioned above (48, 52). Common mental disorders were assessed either by means of the Mini-International Neuropsychiatric Interview (MINI) (57, 58, 67, 70, 71), a structured clinical diagnostic interview according to the DSM-IV and ICD-10, or the CIDI (43, 60). One group of experts based their evaluation of axis-I mental disorders on the Structured Clinical Interview for DSM [SCID-I; (64)]; administered by trained psychiatrists. Definitive clinical diagnoses were based on validated diagnostic methods such as DSM-III-R, DSM-IV, DSM-IV-TR, and ICD-10 (40, 46, 68). Seven studies measured alcohol related problems and reported five different screening methods: the CAGE questionnaire (58), the AUDIT questionnaire (40)—a more detailed set of questions developed by the World Health Organization (WHO) to detect hazardous drinking—MINI standard interviews (56, 62), structured psychiatric interviews focused on alcohol abuse based on the DSM-III or DSM-IV (50, 57, 71), and the SCID-I (40).

Prevalence of Psychiatric Disorders: PTSD, Depression, and Anxiety Disorders

PTSD, depression, and anxiety disorders were the most common psychiatric illnesses investigated. However, prevalence rates of PTSD were disproportionately represented in 30 studies and consistently high: data varied between 2.2 and 88.3% (64). We found depression and anxiety disorders to be the second and third most commonly reported mental disorders among IDPs and refugees: specific estimates varied from 5.1 to 81% for depression (10, 11, 3643, 4548, 5055, 57, 58, 6065, 68, 71) and from 1 to 90% for anxiety disorders (10, 11, 3639, 41, 42, 4446, 4852, 54, 55, 5767, 69, 70). Estimates of more precise diagnoses of anxiety disorders were compatible with the high prevalence of unspecified anxiety among displaced populations. One study showed that generalized anxiety disorder, social phobia, and obsessive-compulsive disorder affected 23, 14, and 5%, respectively, of a sample of 1,876 long-term IDPs in Central Sudan (58).

Prevalence of Psychiatric Disorders: Common Mental Disorders

Fifteen studies looked beyond the general concepts of trauma, PTSD, anxiety, and depression in settings of conflict-related forced displacement (40, 43, 44, 46, 49, 5664, 67, 69, 71). These studies considered additional conditions such as substance abuse, psychosis, suicidality, personality disorders, and other forms of mood and anxiety disorders.

Alcohol use disorders were the most common type of substance abuse reported and were particularly prevalent among displaced men (2–60%) (40, 5658, 62, 64). A Croatian study described rates of non-comorbid alcohol dependence as high as 60.5% (40). Conversely, although drug abuse reached 20% in one recent survey assessing common mental disorders (CMD) in a mixed population of IDPs and refugees in South-western Nigeria (57), drug abuse generally did not exceed 2% (58, 60, 71).

Psychotic disorders were explored in two different samples of African IDPs and refugees and one selected group of refugees in Lebanon: data were heterogeneous and prevalence ranged between 1 and 12% (46, 58, 67). Psychotic symptoms such as visual or auditory hallucinations, however, presented in one African study were as high as 13 and 21%, respectively (57).

We identified four studies completed in Sudan, Southwestern Nigeria, and Lebanon that investigated suicidality, representing a population of 4,447 adult IDPs and refugees (49, 57, 58, 67). In one recent study conducted in a refugee camp in Lebanon by the French NGO Médecins sans Frontières, current rates of suicidality reached 12% (67). Similar results were observed in a Nigerian refugee camp (57). A survey examining the health status of internally displaced adult females in Darfur reported a prevalence rate of 2% for more specific suicidal behaviors, namely attempted or committed suicide (49).

Prevalence of pain disorders was 29% in a group of 392 non-tortured Bhutanese refugees in Nepal (43). Similarly, somatoform disorders were examined in only one survey, conducted in Sri Lanka, and found to affect 14% of 450 IDPs (60).

Discussion

In recent years, there has been a growing interest in research activities related to the psychiatric health sequela of armed conflicts. The high number of people affected globally by organized violence and the low level of available knowledge justify the growth in both quality and quantity of these activities. This systematic review examined for the first time the prevalence of common and uncommon psychiatric disorders among IDPs and refugees displaced as a consequence of armed conflicts in LMICs. The results suggest that PTSD, depression and anxiety disorder are highly prevalent after displacement and armed conflicts. This association can be partially accounted for by distinct psychosocial vulnerabilities of IDP and refugee populations.

This review highlights a lack of studies assessing the prevalence of mental health disorders among forcibly displaced populations in conflict-affected middle–eastern countries as only six studies originated from these regions. This result is particularly striking in view of the ever-changing and ever-increasing figures of worldwide forced migration. For example, according to a 2017 UNHCR report (60), countries such as Turkey, Pakistan, Lebanon, or the Islamic Republic of Iran hosted more than 28% of the world's refugees, people who had been affected from the ongoing conflicts in the Syrian Arab Republic or Afghanistan.

The detailed analysis of the studies included in this review showed a high variability in the duration of displacements between studies. However, we observed that the UNHCR definition of protracted situation was never used as a strict methodological consideration. Rates of trauma exposure were found to be not only high in terms of prevalence but also in terms of recurrence and intensity: all participants included in the reviewed studies had experienced or witnessed at least one serious traumatic event. Thirty-one studies were conducted in populations displaced from countries with a PTS score of four or five. Although prevalence of disorders reported across these countries were heterogeneous, the point estimates for those displaced from countries with a PTS score of less than three were on average lower than those in the highest two PTS quintiles. Understanding how unstable political situations with forced displacement relate to heightened rates of CMDs could inform the development of targeted interventions. Women tended to be over-represented in the studies included in this review, irrespective of their displacement status. This is in line with other literature in refugee and IDP populations (73). The traumas faced after displacement differ between men and women, and the effects of these traumas may manifest different (74). Additionally, this may have caused variance in the reported prevalence's of common psychiatric disorders, which have been shown to differ between men and women (e.g., substance-abuse disorders and depression) (75).

Our findings confirm a long-standing inclination of mental health research toward PTSD, depression, and anxiety disorders in settings of complex emergencies. Public mental health research conducted over the past 20 years has largely focused on the immediate psychological aftermaths of armed conflicts in light of the well-described associations between these psychiatric disorders, displacement, and generalized forms of violence. Demographic and socio-economic characteristics of displaced populations are known to be potent moderators of mental health: migration, especially internal displacement, protracted conflict situations, and economic instability are strongly associated with poor mental health outcomes (5).

We point out a substantial lack of data concerning the general mental health conditions of forcibly displaced populations in LMICs, which might be caused by different mechanisms (28): (1) stigma of mental disorders in developing countries, (2) disproportionate under-representation of several conflict-affected regions in the literature—such as Latin America, Central and Eastern Africa, Central Asia—(3) cultural or political barriers to assessment and implementation of mental health programs and policies such as insufficient funding of mental health research, (4) over-centralization of mental health resources, (5) severe shortage of adequately trained mental health staff, and, finally, (6) weak public health leadership in the field of mental health. The very few estimates about substance abuse, other mood and anxiety disorders, psychosis, or suicidality are higher than figures from the general population studies conducted in LMICs (13, 14, 7684).

Lastly, there is a relative consensus on how to assess common mental disorders among IDPs and refugees. Structured questionnaires such as the HSCL-25, HTQ, PCL, and CIDI are largely favored for the evaluation of PTSD, depression, and anxiety disorders; they are also systematically examined for cultural validity, translated into the participants' native language, and administered by trained lay people, mental health specialists or medical practitioners. Conversely, other forms of mental disturbances such as psychosis or suicidality are assessed through MINI or SCID interviews with the help of the DSM or ICD for diagnosis validation.

Limitations

This review has a number of limitations and should therefore be interpreted cautiously. Despite our systematic search strategy, it is likely that certain unpublished or non-indexed studies have not been included. We did not establish direct contacts with authors in order to identify additional studies. Furthermore, the generalizability of our results to the entire IDP or refugee population is limited. Most research groups have favored the cross-sectional study that has been repeatedly criticized for its limitations in terms of selection bias and causality analysis (8587). The proportion of psychiatric cases pre-existing the conflict and directly caused or at least influenced by armed conflicts and subsequent displacements remains unclear due to a lack of mental health programs in LMICs.

The presented results were extracted from studies conducted in several regions that differ greatly in terms of population characteristics, culture, social traditions, religion, language, and even types of conflict or duration of displacement. No meta-analysis has been undertaken, therefore, inter-study variability and publication bias have not been examined, and heterogeneity has not been significantly reduced. Moreover, the cross-cultural aspect of a majority of studies may have influenced the final results (88).

The HSCL-25 and HTQ have been extensively used to assess depression, anxiety disorders, and PTSD among IDP sub-populations and refugees, but not validated for general populations in LMICs (89). Many validation studies have been conducted in novel contexts for these scales and others, but it is imperative that cultural adaptations be completed prior to their use in novel contexts (33, 90). In addition, both the HSCL-25 and the HTQ only report on symptoms. Therefore, it remains unclear to what extent these symptoms would correlate with formal clinical diagnoses based on the DSM or ICD.

Finally, some of studies did not specify whether any cultural adaptation was undertaken to formulate diagnostic criteria. Psychiatric presentation and diagnosis (including the criteria outlined in the DSM and ICD), are known to exhibit cross-cultural differences (91). Due to the recent refugee and humanitarian crises, psychometric measures and clinical interviews used to ascertain the presence of CMDs (i.e., depression, anxiety, and PTSD) in refugee populations have been widely studied and validated (92). In relation to the severe and uncommon disorders reported in this study, there is a paucity of research in the refugee context. As such, it is possible that authors used culturally unadapted methods to determine diagnosis and that estimated prevalence rates may not be representative of the true values in the populations studied.

Practical Implications and Conclusion

Wars and other forms of organized violence generally draw the attention of policymakers, mass media, and non-governmental organizations. Mental health and public health experts tend to consider this selective and often temporary attention as an opportunity to raise awareness about the psychological consequences of armed conflicts, namely PTSD, to warn about the disastrous mental health situation in low- and middle-income countries. With the numbers of displaced individuals reaching unprecedented levels, a more global mental health approach is necessary to effectively support affected nations. In places where violence is seen as a necessary factor in achieving peace, ongoing armed conflict, and displacement will likely contribute to continued psychological impairment and suffering among those affected (50). Allowing for a better understanding of the effects that the aftermath of war have on the psychological well-being will allow for interventions not only targeting mental illness but also attitudes toward reconciliation and justice and reduction of future violence (93).

In sum, this systematic review indicates that the heterogeneity in prevalence rates is caused by methodological differences between studies and differences between conflict-affected IDP and refugee populations. We recommend that future public mental health research goes beyond the assessment of PTSD, depression, and anxiety disorders and consider a broader inclusive definition of the psychological consequences of armed conflict as additional key concept. In addition to that questionnaires assessing more severe disorders (e.g., psychotic disorders) which are often ignored need to be developed and validated for use in LMICs.

Ambitious and locally coordinated assessment programs of mental health should be implemented as well as non-centralized mental health policies and their systematic qualitative evaluations (94). Lastly, the on-going crises indicate that there is an urgent need for scalable interventions that are appropriate for war-torn contexts in which resources are limited. The World Health Organization is currently spearheading this with the so called low-intensity intervention Problem Management Plus [PM+; (95)] being the most evidence-based release to date (96, 97). On-going research is aiming to increase the scope of this intervention to allow for group-based and application-based administration. However, the most critical challenge will be to translate these promising intervention programs into sustainable public mental health policies in countries so deeply weakened by protracted conflicts, destruction of fragile pre-existing health care structures, and political instability. Finally, it is unfortunately common that refugees and IDPs are not being treated fairly wherever they end up seeking protection and support, and are subjected to ongoing humiliating, traumatizing, or otherwise damaging circumstances. From a societal and ethical viewpoint, changing these circumstances may even constitute a higher priority than diagnosing and treating trauma-related mental illness.

Author Contributions

All authors contributed to the study conception and design. AA and NM conducted literature search and data extraction. NM and AA performed data analyses and drafted the manuscript. All authors contributed to and approved the final version of the manuscript.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Acknowledgments

We would like to acknowledge Laurent Levy's help in preliminary screening of the literature and data extraction.

References

1. Orend B. War. In: Zalta EN, editor. The Stanford Encyclopedia of Philosophy. Fall (2008). Available online at: https://plato.stanford.edu/archives/fall2008/entries/war/

Google Scholar

2. Allansson M, Melander E, Themnér L. Organized violence, 1989–2016. J Peace Res. (2017) 54:574–87. doi: 10.1177/0022343317718773

CrossRef Full Text | Google Scholar

3. Spiegel PB, Checchi F, Colombo S, Paik E. Health-care needs of people affected by conflict: future trends and changing frameworks. Lancet (2010) 375:341–5. doi: 10.1016/S0140-6736(09)61873-0

PubMed Abstract | CrossRef Full Text | Google Scholar

4. Hall BJ, Olff M. Global mental health: trauma and adversity among populations in transition. Eur J Psychotraumatol. (2016) 7. doi: 10.3402/ejpt.v7.31140

PubMed Abstract | CrossRef Full Text | Google Scholar

5. UNHCR. Global trends UNHCR 2016 2017. Available online at: http://www.unhcr.org/5943e8a34.pdf (Accessed December 20, 2016).

6. IDCP. Global Overview 2016: People Internally Displaced by Conflict and Violence (2017).

7. Spiegel PB, Qassim M. Forgotten refugees and other displaced populations. Lancet (2003) 362:72–4. doi: 10.1016/S0140-6736(03)13812-3

PubMed Abstract | CrossRef Full Text | Google Scholar

8. Salama P, Spiegel P, Talley L, Waldman R. Lessons learned from complex emergencies over past decade. Lancet (2004) 364:1801–13. doi: 10.1016/S0140-6736(04)17405-9

PubMed Abstract | CrossRef Full Text | Google Scholar

9. Mollica RF, Sarajlic N, Chernoff M, Lavelle J, Vukovic IS, Massagli MP. Longitudinal study of psychiatric symptoms, disability, mortality, and emigration among Bosnian refugees. JAMA (2001) 286:546–54. doi: 10.1001/jama.286.5.546

PubMed Abstract | CrossRef Full Text | Google Scholar

10. Sabin M, Lopes Cardozo B, Nackerud L, Kaiser R, Varese L. Factors associated with poor mental health among Guatemalan refugees living in Mexico 20 years after civil conflict. JAMA (2003) 290:635–42. doi: 10.1001/jama.290.5.635

PubMed Abstract | CrossRef Full Text | Google Scholar

11. Roberts B, Damundu EY, Lomoro O, Sondorp E. Post-conflict mental health needs: a cross-sectional survey of trauma, depression and associated factors in Juba, Southern Sudan. BMC Psychiatry (2009) 9:7. doi: 10.1186/1471-244X-9-7

PubMed Abstract | CrossRef Full Text | Google Scholar

12. IDCP. Global Overview 2014: People Internally Displaced by Conflict and Violence (2015).

13. Mollica RF, Cardozo BL, Osofsky HJ, Raphael B, Ager A, Salama P. Mental health in complex emergencies. Lancet (2004) 364:2058–67. doi: 10.1016/S0140-6736(04)17519-3

PubMed Abstract | CrossRef Full Text | Google Scholar

14. Tol WA, Barbui C, Galappatti A, Silove D, Betancourt TS, Souza R, et al. Mental health and psychosocial support in humanitarian settings: linking practice and research. Lancet (2011) 378:1581–91. doi: 10.1016/S0140-6736(11)61094-5

PubMed Abstract | CrossRef Full Text | Google Scholar

15. Turner S. Refugee blues: a UK and European perspective. Eur J Psychotraumatol. (2015) 6:29328. doi: 10.3402/ejpt.v6.29328

PubMed Abstract | CrossRef Full Text | Google Scholar

16. Steel Z, Chey T, Silove D, Marnane C, Bryant RA, van Ommeren M. Association of torture and other potentially traumatic events with mental health outcomes among populations exposed to mass conflict and displacement: a systematic review and meta-analysis. JAMA (2009) 302:537–49. doi: 10.1001/jama.2009.1132

PubMed Abstract | CrossRef Full Text | Google Scholar

17. Ezard N. Substance use among populations displaced by conflict: a literature review. Disasters (2012) 36:533–57. doi: 10.1111/j.1467-7717.2011.01261.x

PubMed Abstract | CrossRef Full Text | Google Scholar

18. Moher D, Liberati A, Tetzlaff J, Altman DG, The Prisma Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. (2009) 6:e1000097. doi: 10.1371/journal.pmed.1000097

CrossRef Full Text | Google Scholar

19. The PILOTS Database [Internet]. National Center for PTSD. U.S. Department of Veterans Affairs (2015) (Accessed June 15, 2015). Available online at: http://www.ptsd.va.gov/professional/pilots-database/

20. Betancourt TS, Speelman L, Onyango G, Bolton P. A qualitative study of mental health problems among children displaced by war in northern Uganda. Transcult Psychiatry (2009) 46:238–56. doi: 10.1177/1363461509105815

PubMed Abstract | CrossRef Full Text | Google Scholar

21. Fazel M, Reed RV, Panter-Brick C, Stein A. Mental health of displaced and refugee children resettled in high-income countries: risk and protective factors. Lancet (2012) 379:266–82. doi: 10.1016/S0140-6736(11)60051-2

PubMed Abstract | CrossRef Full Text | Google Scholar

22. Reed RV, Fazel M, Jones L, Panter-Brick C, Stein A. Mental health of displaced and refugee children resettled in low-income and middle-income countries: risk and protective factors. Lancet (2012) 379:250–65. doi: 10.1016/S0140-6736(11)60050-0

PubMed Abstract | CrossRef Full Text | Google Scholar

23. Tol WA, Song S, Jordans MJ. Annual Research Review: resilience and mental health in children and adolescents living in areas of armed conflict–a systematic review of findings in low- and middle-income countries. J Child Psychol Psychiatry (2013) 54:445–60. doi: 10.1111/jcpp.12053

PubMed Abstract | CrossRef Full Text | Google Scholar

24. Patel V. Global mental health: from science to action. Harvard Rev Psychiatry (2012) 20:6–12. doi: 10.3109/10673229.2012.649108

PubMed Abstract | CrossRef Full Text | Google Scholar

25. State TUSDo. Secretary for Civilian Security, Democracy, and Human Rights. Bureau of Population, Refugees, and Migration (2015).

26. Bank TW. Country and Lending Groups. Washington, DC (2014).

27. Fazel M, Wheeler J, Danesh J. Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review. Lancet (2005) 365:1309–14. doi: 10.1016/S0140-6736(05)61027-6

PubMed Abstract | CrossRef Full Text | Google Scholar

28. Porter M, Haslam N. Predisplacement and postdisplacement factors associated with mental health of refugees and internally displaced persons: a meta-analysis. JAMA (2005) 294:602–12. doi: 10.1001/jama.294.5.602

PubMed Abstract | CrossRef Full Text | Google Scholar

29. UNHCR. The UN Refugee Agency (2014).

30. Feldman JS. Development Assisted Integration: A Viable Alternative to Long Term Residence in Refugee Camps (2007).

31. APA. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV. 4 ed. Washington, DC: APA (1994).

32. Dilling H, Mombour W, Schmidt MH (eds). Internationale Klassifikation psychischer Störungen. ICD-10 Kapitel V (F). Klinisch Diagnostische Leitlinien. Bern: Huber (1993).

Google Scholar

33. Mollica RF, Caspi-Yavin Y, Bollini P, Truong T, Tor S, Lavelle J. The Harvard Trauma Questionnaire. Validating a cross-cultural instrument for measuring torture, trauma, and posttraumatic stress disorder in Indochinese refugees. J Nerv Ment Dis. (1992) 180:111–6.

PubMed Abstract | Google Scholar

34. Mollica RF, Wyshak G, Marneffe DD, Tu B, Yang T, Khuon F, et al. Hopkins Symptom Checklist 25. Manual: Harvard Program in Refugee Trauma: Harvard School of Public Health (1991).

Google Scholar

35. Gibney M, Linda C, Reed W, Peter H, Daniel A. The Political Terror Scale 1976-2012. (2014). Available online at: http://www.politicalterrorscale.org/about.php

36. Mollica RF, Donelan K, Tor S, Lavelle J, Elias C, Frankel M, et al. The effect of trauma and confinement on functional health and mental health status of Cambodians living in Thailand-Cambodia border camps. JAMA (1993) 270:581–6.

PubMed Abstract | Google Scholar

37. Allden K, Poole C, Chantavanich S, Ohmar K, Aung NN, Mollica RF. Burmese political dissidents in Thailand: trauma and survival among young adults in exile. Am J Public Health (1996) 86:1561–9.

PubMed Abstract | Google Scholar

38. Mollica RF, McInnes K, Sarajlic N, Lavelle J, Sarajlic I, Massagli MP. Disability associated with psychiatric comorbidity and health status in Bosnian refugees living in Croatia. JAMA (1999) 282:433–9.

PubMed Abstract | Google Scholar

39. Peltzer K. Trauma and mental health problems of Sudanese refugees in Uganda. Centr Afr J Med. (1999) 45:110–4.

PubMed Abstract | Google Scholar

40. Kozaric-Kovacic D, Ljubin T, Grappe M. Comorbidity of posttraumatic stress disorder and alcohol dependence in displaced persons. Croat Med J. (2000) 41:173–8.

PubMed Abstract | Google Scholar

41. Lee Y, Lee MK, Chun KH, Lee YK, Yoon SJ. Trauma experience of North Korean refugees in China. Am J Prev Med. (2001) 20:225–9. doi: 10.1016/S0749-3797(00)00282-8

PubMed Abstract | CrossRef Full Text | Google Scholar

42. Tang SS, Fox SH. Traumatic experiences and the mental health of Senegalese refugees. J Nerv Ment Dis. (2001) 189:507-12.

PubMed Abstract | Google Scholar

43. van Ommeren M, de Jong JT, Sharma B, Komproe I, Thapa SB, Cardena E. Psychiatric disorders among tortured Bhutanese refugees in Nepal. Arch Gen Psychiatry (2001) 58:475-82. doi: 10.1001/archpsyc.58.5.475

CrossRef Full Text | Google Scholar

44. Kalafi Y, Hagh-Shenas H, Ostovar A. Mental health among Afghan refugees settled in Shiraz, Iran. Psychol Rep. (2002) 90:262–6. doi: 10.2466/pr0.2002.90.1.262

PubMed Abstract | CrossRef Full Text | Google Scholar

45. Lopes Cardozo B, Talley L, Burton A, Crawford C. Karenni refugees living in Thai-Burmese border camps: traumatic experiences, mental health outcomes, and social functioning. Soc Sci Med. (2004) 58:2637–44. doi: 10.1016/j.socscimed.2003.09.024

CrossRef Full Text | Google Scholar

46. Kamau M, Steel Z, Catanzaro R, Bateman C, Ekblad S. Psychiatric disorders in an African refugee camp. Intervention (2014) 2:84–9.

Google Scholar

47. Karunakara UK, Neuner F, Schauer M, Singh K, Hill K, Elbert T, et al. Traumatic events and symptoms of post-traumatic stress disorder amongst Sudanese nationals, refugees and Ugandans in the West Nile. Afr Health Sci. (2004) 4:83–93.

PubMed Abstract | Google Scholar

48. Thapa SB, Hauff E. Psychological distress among displaced persons during an armed conflict in Nepal. Soc Psychiatry Psychiatr Epidemiol. (2005) 40:672–9. doi: 10.1007/s00127-005-0943-9

PubMed Abstract | CrossRef Full Text | Google Scholar

49. Kim G, Torbay R, Lawry L. Basic health, women's health, and mental health among internally displaced persons in Nyala Province, South Darfur, Sudan. Am J Public Health. (2007) 97:353-61.

PubMed Abstract | Google Scholar

50. Vinck P, Pham PN, Stover E, Weinstein HM. Exposure to war crimes and implications for peace building in northern Uganda. JAMA (2007) 298:543–54. doi: 10.1001/jama.298.5.543

PubMed Abstract | CrossRef Full Text | Google Scholar

51. Roberts B, Ocaka KF, Browne J, Oyok T, Sondorp E. Factors associated with post-traumatic stress disorder and depression amongst internally displaced persons in northern Uganda. BMC Psychiatry (2008) 8:38. doi: 10.1186/1471-244X-8-38

PubMed Abstract | CrossRef Full Text | Google Scholar

52. Onyut LP, Neuner F, Ertl V, Schauer E, Odenwald M, Elbert T. Trauma, poverty and mental health among Somali and Rwandese refugees living in an African refugee settlement - an epidemiological study. Confl Health (2009) 3:6. doi: 10.1186/1752-1505-3-6

PubMed Abstract | CrossRef Full Text | Google Scholar

53. Hamid AA, Musa SA. Mental health problems among internally displaced persons in Darfur. Int J Psychol. (2010) 45:278–85. doi: 10.1080/00207591003692620

PubMed Abstract | CrossRef Full Text | Google Scholar

54. Husain F, Anderson M, Lopes Cardozo B, Becknell K, Blanton C, Araki D, et al. Prevalence of war-related mental health conditions and association with displacement status in postwar Jaffna District, Sri Lanka. JAMA (2011) 306:522–31. doi: 10.1001/jama.2011.1052

PubMed Abstract | CrossRef Full Text | Google Scholar

55. Richards A, Ospina-Duque J, Barrera-Valencia M, Escobar-Rincón J, Ardila-Gutiérrez M, Metzler T, et al. Posttraumatic stress disorder, anxiety and depression symptoms, and psychosocial treatment needs in colombians internally displaced by armed conflict: a mixed-method evaluation. Psychol Trauma Theor Res Pract Policy (2011) 3:384–93. doi: 10.1037/a0022257

CrossRef Full Text | Google Scholar

56. Roberts B, Felix Ocaka K, Browne J, Oyok T, Sondorp E. Alcohol disorder amongst forcibly displaced persons in northern Uganda. Addict Behav. (2011) 36:870–3. doi: 10.1016/j.addbeh.2011.03.006

PubMed Abstract | CrossRef Full Text | Google Scholar

57. Akinyemi OO, Owoaje ET, Ige OK, Popoola OA. Comparative study of mental health and quality of life in long-term refugees and host populations in Oru-Ijebu, Southwest Nigeria. BMC Res Notes (2012) 5:394. doi: 10.1186/1756-0500-5-394

PubMed Abstract | CrossRef Full Text | Google Scholar

58. Salah TT, Abdelrahman A, Lien L, Eide AH, Martinez P, Hauff E. The mental health of internally displaced persons: an epidemiological study of adults in two settlements in Central Sudan. Int J Soc Psychiatry (2013) 59:782–8. doi: 10.1177/0020764012456810

PubMed Abstract | CrossRef Full Text | Google Scholar

59. Doocy S, Sirois A, Tileva M, Storey JD, Burnham G. Chronic disease and disability among Iraqi populations displaced in Jordan and Syria. Int J Health Plann Manage. (2013) 28:e1–e12. doi: 10.1002/hpm.2119

PubMed Abstract | CrossRef Full Text | Google Scholar

60. Siriwardhana C, Adikari A, Pannala G, Siribaddana S, Abas M, Sumathipala A, et al. Prolonged internal displacement and common mental disorders in Sri Lanka: the COMRAID study. PLoS ONE (2013) 8:e64742. doi: 10.1371/journal.pone.0064742

PubMed Abstract | CrossRef Full Text | Google Scholar

61. Makhashvili N, Chikovani I, McKee M, Bisson J, Patel V, Roberts B. Mental disorders and their association with disability among internally displaced persons and returnees in Georgia. J Trauma Stress (2014) 27:509–18. doi: 10.1002/jts.21949

PubMed Abstract | CrossRef Full Text | Google Scholar

62. Roberts B, Murphy A, Chikovani I, Makhashvili N, Patel V, McKee M. Individual and community level risk-factors for alcohol use disorder among conflict-affected persons in Georgia. PLoS ONE (2014) 9:e98299. doi: 10.1371/journal.pone.0098299

PubMed Abstract | CrossRef Full Text | Google Scholar

63. Comellas RM, Makhashvili N, Chikovani I, Patel V, McKee M, Bisson J, et al. Patterns of somatic distress among conflict-affected persons in the Republic of Georgia. J Psychosom Res. (2015) 78:466–71. doi: 10.1016/j.jpsychores.2015.01.015

PubMed Abstract | CrossRef Full Text | Google Scholar

64. Elhabiby MM, Radwan DN, Okasha TA, El-Desouky ED. Psychiatric disorders among a sample of internally displaced persons in South Darfur. Int J Soc Psychiatry (2015) 61:358–62. doi: 10.1177/0020764014547061

PubMed Abstract | CrossRef Full Text | Google Scholar

65. Sheikh TL, Mohammed A, Agunbiade S, Ike J, Ebiti WN, Adekeye O. Psycho-trauma, psychosocial adjustment, and symptomatic post-traumatic stress disorder among internally displaced persons in Kaduna, Northwestern Nigeria. Front Psychiatry (2014) 5:127. doi: 10.3389/fpsyt.2014.00127

PubMed Abstract | CrossRef Full Text | Google Scholar

66. Vukovic IS, Jovanovic N, Kolaric B, Vidovic V, Mollica RF. Psychological and somatic health problems in Bosnian refugees: a three year follow-up. Psychiatr Danub. (2014) 26(Suppl. 3):442–9.

PubMed Abstract | Google Scholar

67. Llosa AE, Ghantous Z, Souza R, Forgione F, Bastin P, Jones A, et al. Mental disorders, disability and treatment gap in a protracted refugee setting. Br J Psychiatry (2014) 204:208–13. doi: 10.1192/bjp.bp.112.120535

PubMed Abstract | CrossRef Full Text | Google Scholar

68. Alpak G, Unal A, Bulbul F, Sagaltici E, Bez Y, Altindag A, et al. Post-traumatic stress disorder among Syrian refugees in Turkey: a cross-sectional study. Int J Psychiatry Clin Pract. (2015) 19:45–50. doi: 10.3109/13651501.2014.961930

PubMed Abstract | CrossRef Full Text | Google Scholar

69. Feyera F, Mihretie G, Bedaso A, Gedle D, Kumera G. Prevalence of depression and associated factors among Somali refugee at Melkadida camp, Southeast Ethiopia: a cross-sectional study. BMC Psychiatry (2015) 15:171. doi: 10.1186/s12888-015-0539-1

PubMed Abstract | CrossRef Full Text | Google Scholar

70. Naja WJ, Aoun MP, El Khoury EL, Abdallah FJ, Haddad RS. Prevalence of depression in Syrian refugees and the influence of religiosity. Compr Psychiatry (2016) 68:78–85. doi: 10.1016/j.comppsych.2016.04.002

PubMed Abstract | CrossRef Full Text | Google Scholar

71. Kazour F, Zahreddine NR, Maragel MG, Almustafa MA, Soufia M, Haddad R, et al. Post-traumatic stress disorder in a sample of Syrian refugees in Lebanon. Compr Psychiatry (2017) 72:41–7. doi: 10.1016/j.comppsych.2016.09.007

PubMed Abstract | CrossRef Full Text | Google Scholar

72. Robins LN, Wing J, Wittchen HU, Helzer JE, Babor TF, Burke J, et al. The composite international diagnostic interview: an epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry (1988) 45:1069–77.

PubMed Abstract | Google Scholar

73. Affleck W, Selvadurai A, Sikora L. Underrepresentation of men in gender based humanitarian and refugee trauma research: a scoping review. Intervention (2018) 16:22–30. doi: 10.1097/WTF.0000000000000157

CrossRef Full Text | Google Scholar

74. Ager A, Ager W, Stavrou V, Boothby N. Inter-Agency Guide to the Evaluation of Psychosocial Programming in Emergencies. New York, NY: UNICEF (2011).

Google Scholar

75. Kessler RC, Amminger GP, Aguilar-Gaxiola S, Alonso J, Lee S, Ustun TB. Age of onset of mental disorders: a review of recent literature. Curr Opin Psychiatry (2007) 20:359–64. doi: 10.1097/YCO.0b013e32816ebc8c

PubMed Abstract | CrossRef Full Text | Google Scholar

76. Pincock S. Vikram Patel: promoting mental health in developing countries. Lancet (2007) 370:821. doi: 10.1016/S0140-6736(07)61400-7

PubMed Abstract | CrossRef Full Text | Google Scholar

77. Herrman H, Swartz L. Promotion of mental health in poorly resourced countries. Lancet (2007) 370:1195–7. doi: 10.1016/S0140-6736(07)61244-6

PubMed Abstract | CrossRef Full Text | Google Scholar

78. Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR, et al. No health without mental health. Lancet (2007) 370:859–77. doi: 10.1016/S0140-6736(07)61238-0

PubMed Abstract | CrossRef Full Text | Google Scholar

79. Saxena S, Thornicroft G, Knapp M, Whiteford H. Resources for mental health: scarcity, inequity, and inefficiency. Lancet (2007) 370:878–89. doi: 10.1016/S0140-6736(07)61239-2

PubMed Abstract | CrossRef Full Text | Google Scholar

80. Chisholm D, Flisher AJ, Lund C, Patel V, Saxena S, Thornicroft G, et al. Scale up services for mental disorders: a call for action. Lancet (2007) 370:1241–52. doi: 10.1016/S0140-6736(07)61242-2

PubMed Abstract | CrossRef Full Text | Google Scholar

81. Eaton J, McCay L, Semrau M, Chatterjee S, Baingana F, Araya R, et al. Scale up of services for mental health in low-income and middle-income countries. Lancet (2011) 378:1592–603. doi: 10.1016/S0140-6736(11)60891-X

PubMed Abstract | CrossRef Full Text | Google Scholar

82. Drew N, Funk M, Tang S, Lamichhane J, Chavez E, Katontoka S, et al. Human rights violations of people with mental and psychosocial disabilities: an unresolved global crisis. Lancet (2011) 378:1664–75. doi: 10.1016/S0140-6736(11)61458-X

PubMed Abstract | CrossRef Full Text | Google Scholar

83. Saraceno B, van Ommeren M, Batniji R, Cohen A, Gureje O, Mahoney J, et al. Barriers to improvement of mental health services in low-income and middle-income countries. Lancet (2007) 370:1164–74. doi: 10.1016/S0140-6736(07)61263-X

PubMed Abstract | CrossRef Full Text | Google Scholar

84. Alisic E, Letschert RM. Fresh eyes on the European refugee crisis. Eur J Psychotraumatol. (2016) 7:2016. doi: 10.3402/ejpt.v7.31847

PubMed Abstract | CrossRef Full Text | Google Scholar

85. Jones L, Asare JB, El Masri M, Mohanraj A, Sherief H, van Ommeren M. Severe mental disorders in complex emergencies. Lancet (2009) 374:654–61. doi: 10.1016/S0140-6736(09)61253-8

PubMed Abstract | CrossRef Full Text | Google Scholar

86. Patel V. Mental health in low- and middle-income countries. Br Med Bull. (2007) 81–82:81–96. doi: 10.1093/bmb/ldm010

CrossRef Full Text | Google Scholar

87. Karam EG, Mneimneh ZN, Karam AN, Fayyad JA, Nasser SC, Chatterji S, et al. Prevalence and treatment of mental disorders in Lebanon: a national epidemiological survey. Lancet (2006) 367:1000–6. doi: 10.1016/S0140-6736(06)68427-4

PubMed Abstract | CrossRef Full Text | Google Scholar

88. Armitage P. Statistical Methods in Medical Research. Oxford; Malden, MA: Blackwell Science (2002).

Google Scholar

89. Bracken PJ, Giller JE, Summerfield D. Psychological responses to war and atrocity: the limitations of current concepts. Soc Sci Med. (1995) 40:1073–82. doi: 10.1016/0277-9536(94)00181-R

PubMed Abstract | CrossRef Full Text | Google Scholar

90. Mills EJ, Singh S, Holtz TH, Chase RM, Dolma S, Santa-Barbara J, et al. Prevalence of mental disorders and torture among Tibetan refugees: a systematic review. BMC Int Health Hum Rights (2005) 5:7. doi: 10.1186/1472-698X-5-7

PubMed Abstract | CrossRef Full Text | Google Scholar

91. Summerfield D. Afterword: against “global mental health”. Trans Psychiatry (2012) 49:519–30. doi: 10.1177/1363461512454701

PubMed Abstract | CrossRef Full Text | Google Scholar

92. Johnson H, Thompson A. The development and maintenance of post-traumatic stress disorder (PTSD) in civilian adult survivors of war trauma and torture: a review. Clin Psychol Rev. (2008) 28:36–47. doi: 10.1016/j.cpr.2007.01.017

PubMed Abstract | CrossRef Full Text | Google Scholar

93. Pham PN, Weinstein HM, Longman T. Trauma and PTSD symptoms in Rwanda: implications for attitudes toward justice and reconciliation. JAMA (2004) 292:602–12. doi: 10.1001/jama.292.5.602

PubMed Abstract | CrossRef Full Text | Google Scholar

94. Nickerson A, Liddell B, Asnaani A, Carlsson JM, Fazel M, Knaevelsrud C, et al. Trauma and Mental Health in Forcibly Displaced Populations: An International Society for Traumatic Stress Studies Briefing Paper (2017).

95. World Health Organization. Problem Management Plus (PM+): Individual Psychological Help for Adults Impaired by Distress in Communities Exposed to Adversity. Geneva: WHO (2016). 140.

Google Scholar

96. Bryant RA, Schafer A, Dawson KS, Anjuri D, Mulili C, Ndogoni L, et al. Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya: a randomised clinical trial. PLoS Med. (2017) 14:e1002371. doi: 10.1371/journal.pmed.1002371

PubMed Abstract | CrossRef Full Text | Google Scholar

97. Rahman A, Riaz N, Dawson KS, Usman Hamdani S, Chiumento A, Sijbrandij M, et al. Problem Management Plus (PM+): pilot trial of a WHO transdiagnostic psychological intervention in conflict-affected Pakistan. World Psychiatry (2016) 15:182–3. doi: 10.1002/wps.20312

PubMed Abstract | CrossRef Full Text | Google Scholar

Keywords: mental health, psychiatric disorders, refugees, internally displaced people, epidemiology, war, systematic review

Citation: Morina N, Akhtar A, Barth J and Schnyder U (2018) Psychiatric Disorders in Refugees and Internally Displaced Persons After Forced Displacement: A Systematic Review. Front. Psychiatry 9:433. doi: 10.3389/fpsyt.2018.00433

Received: 14 May 2018; Accepted: 23 August 2018;
Published: 21 September 2018.

Edited by:

Michael P. Hengartner, Zurich University of Applied Sciences, Switzerland

Reviewed by:

Andrew Clifton, De Montfort University, United Kingdom
Jon Jureidini, University of Adelaide, Australia

Copyright © 2018 Morina, Akhtar, Barth and Schnyder. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Naser Morina, bmFzZXIubW9yaW5hQHVzei5jaA==

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.