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CORRECTION article

Front. Physiol., 09 December 2021
Sec. Renal Physiology and Pathophysiology

Corrigendum: Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation

\nSiqing Ma,,,Siqing Ma1,2,3,4Heng XuHeng Xu5Weihua Huang,,,Weihua Huang1,2,3,4Yongchao Gao,,,Yongchao Gao1,2,3,4Honghao Zhou,,,Honghao Zhou1,2,3,4Xiong Li
Xiong Li6*Wei Zhang,,,
Wei Zhang1,2,3,4*
  • 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China
  • 2Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, China
  • 3Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, Changsha, China
  • 4National Clinical Research Center for Geriatric Disorders, Changsha, China
  • 5Department of Laboratory Medicine, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China
  • 6The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangdong, China

A Corrigendum on
Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation

by Ma, S., Xu, H., Huang, W., Gao, Y., Zhou, H., Li X and Zhang W. (2021). Front. Physiol. 12:706359. doi: 10.3389/fphys.2021.706359

Error in Figure

In the original article, there was a mistake in Figure 4 as published. The wrong figure was published. The corrected capillary blot of BAX and GAPDH in Figure 4F is now consistent with the original data submitted during initiation validation process. The corrected Figure 4 appears below.

FIGURE 4
www.frontiersin.org

Figure 4. Chrysophanol pretreatment relieved CDDP-induced nephritic apoptosis of C57 mice via inhibition of p53 activation. (A) Representative graphs of IHC with c-caspase 3 antibody. (B) Semi-quantification and statistical analysis of c-caspase 3 expression for IHC staining in kidney tissues. (C) Caspase 3 mRNA expression. (D) Bax mRNA expression. (E) Bcl-2 mRNA expression. (F) The protein expression of p-p53, BCL-2, BAX, and GAPDH detected by capillary blot. (G) Quantitative and statistical analysis of relative p-p53 level in kidneys. (H) Quantitative and statistical analysis of relative BCL-2 level in kidneys. (I) Quantitative and statistical analysis of relative BAX level in kidneys. *p < 0.05, **p < 0.01, and ***p < 0.005. ns, no statistical difference.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: chrysophanol, cisplatin, acute kidney injury, oxidative stress, apoptosis, inflammation

Citation: Ma S, Xu H, Huang W, Gao Y, Zhou H, Li X and Zhang W (2021) Corrigendum: Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation. Front. Physiol. 12:794302. doi: 10.3389/fphys.2021.794302

Received: 13 October 2021; Accepted: 26 November 2021;
Published: 09 December 2021.

Edited and reviewed by: James A. McCormick, Oregon Health and Science University, United States

Copyright © 2021 Ma, Xu, Huang, Gao, Zhou, Li and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Xiong Li, bGl4aW9uZyYjeDAwMDQwO2dkcHUuZWR1LmNu; Wei Zhang, Y3N1emhhbmd3ZWkmI3gwMDA0MDtjc3UuZWR1LmNu

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.