Fucoidan Ameliorates Renal Injury-Related Calcium-Phosphorus Metabolic Disorder and Bone Abnormality in the CKD–MBD Model Rats by Targeting FGF23-Klotho Signaling Axis
- 1Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- 2Nephrology Division, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
- 3The School of Pharmacy, Management and Science University, Shah Alam, Malaysia
- 4Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
- 5Department of Traditional Chinese Medicine Health Preservation, Acupuncture, Moxibustion and Massage College, Health Preservation and Rehabilitation College, Nanjing University of Chinese Medicine, Nanjing, China
- 6Department of Social Work, Meiji Gakuin University, Tokyo, Japan
- 7Jilin Province Huinan Chonglong Bio-Pharmacy Co., Ltd., Huinan, China
by Liu B-H, Chong F-L, Yuan C-C, Liu Y-L, Yang H-M, Wang W-W, Fang Q-J, Wu W, Wang M-Z, Tu Y, Wan Z-Y, Wan Y-G and Wu G-W (2021). Front. Pharmacol. 11:586725. doi: 10.3389/fphar.2020.586725
In the published article, there was an error in Figure 5 as published. One image was erroneously overlapped in Figure 5A -FGF23-Sham + Vehicle, and in Figure 5A -FGF23-CKD-MBD + CTR. The corrected Figure 5 and its caption appear below.
Figure 5. FPS and CTR regulated FGF23-Klotho signaling axis in vivo (A) The protein expressional characteristics of Klotho, FGF23 and FGFR1 in renal tubulointerstitium of the kidneys in the four group rats. IHC staining × 200. Scale bar 100 µm (B) The protein expressional levels of Klotho, FGF23 and FGFR1 in the kidney of the four group rats (C) The rate of Klotho/GAPDH (D) The rate of FGF23/GAPDH (E) The rate of FGFR1/GAPDH. The data are expressed as mean ± S.D. **p < 0.01.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: fucoidan, chronic kidney disease-mineral and bone disorder, FGF23-klotho signaling axis, phosphorus reabsorption, ERK1/2-SGK1-NHERF-1-NaPi-2a pathway
Citation: Liu B-H, Chong F-L, Yuan C-C, Liu Y-L, Yang H-M, Wang W-W, Fang Q-J, Wu W, Wang M-Z, Tu Y, Wan Z-Y, Wan Y-G and Wu G-W (2024) Corrigendum: Fucoidan ameliorates renal injury-related calcium-phosphorus metabolic disorder and bone abnormality in the CKD–MBD model rats by targeting FGF23-Klotho signaling axis. Front. Pharmacol. 15:1446609. doi: 10.3389/fphar.2024.1446609
Received: 10 June 2024; Accepted: 25 June 2024;
Published: 23 July 2024.
Edited and reviewed by:
Jianping Chen, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, ChinaCopyright © 2024 Liu, Chong, Yuan, Liu, Yang, Wang, Fang, Wu, Wang, Tu, Wan, Wan and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Yi-Gang Wan, wyg68918@sina.com; Guo-Wen Wu, jl-wgw@163.com
†These authors have contributed equally to this work and share first authorship
‡These authors have contributed equally to this work and share last authorship