This article is a correction to:
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis
Prakriti Mishra1
Mohammad Faizan Ali Ahmad1
Lamya Ahmed Al-Keridis2*
Mohd Saeed3Nawaf Alshammari3
Nadiyah M. Alabdallah4,5
Rohit Kumar Tiwari1,6
Afza Ahmad1
Mahima Verma1Shireen Fatima1
Irfan Ahmad Ansari1*- 1Department of Biosciences Integral University Lucknow, Lucknow, India
- 2Biology Department, Faculty of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia
- 3Department of Biology, College of Science, University of Hail, Hail, Saudi Arabia
- 4Department of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
- 5Basic and Applied Scientific Research Centre, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
- 6Department of Clinical Research, School of Allied Health Sciences, Sharda University, Uttar Pradesh, India
A Corrigendum on
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis
by Mishra P, Ali Ahmad MF, Al-Keridis LA, Saeed M, Alshammari N, Alabdallah NM, Tiwari RK, Ahmad A, Verma M, Fatima S and Ansari IA (2023). Front. Pharmacol. 14:1194578. doi: 10.3389/fphar.2023.1194578
In the published article, there was an error in Figure 8 as published. Partial overlap between the IC50-ZnONPs, IC50-MTX, and IC50-MTX-ZnONPs panels were unintentionally duplicated. The corrected Figure 8 and its caption appear below.
Figure 8
Figure 8. Qualitative evaluation of ROS in H2DCFDA-stained A549 cells treated at IC25 (ZnONPs 27.83 μg/mL; MTX 1.95 μg/mL; and MTX-ZnONPs 182 ng/mL), IC50 (ZnONPs 65.30 μg/mL; MTX 3.58 μg/mL; and MTX-ZnONPs 327 ng/mL), and IC75 (ZnONPs 70.41 μg/mL; MTX 6.57 μg/mL; and MTX-ZnONPs 588 ng/mL) concentrations for 24 h analyzed by fluorescence microscopy. Images shown are representative of three independent experiments (scale bar: 100 μm; magnification: ×20). The control image was reused in each treatment group.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: zinc oxide, nanoparticles, methotrexate, lung cancer, A549, reactive oxygen species, caspases
Citation: Mishra P, Ali Ahmad MF, Al-Keridis LA, Saeed M, Alshammari N, Alabdallah NM, Tiwari RK, Ahmad A, Verma M, Fatima S and Ansari IA (2024) Corrigendum: Methotrexate-conjugated zinc oxide nanoparticles exert substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis. Front. Pharmacol. 15:1423402. doi: 10.3389/fphar.2024.1423402
Received: 25 April 2024; Accepted: 16 July 2024;
Published: 29 July 2024.
Edited and reviewed by:
Vijayakumar Sekar, Shandong University, ChinaCopyright © 2024 Mishra, Ali Ahmad, Al-Keridis, Saeed, Alshammari, Alabdallah, Tiwari, Ahmad, Verma, Fatima and Ansari. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Lamya Ahmed Al-Keridis, laalkeridis@pnu.edu.sa; Irfan Ahmad Ansari, ahmadirfan.amu@gmail.com