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CORRECTION article

Front. Pharmacol., 15 March 2021
Sec. Inflammation Pharmacology
Volume 12 - 2021 | https://doi.org/10.3389/fphar.2021.652905
This article is part of the Research Topic Chronic Inflammation and Neurodegeneration in Retinal Disease View all 12 articles

Corrigendum: Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate with Differences in the Expression of Selected Retinal miRNAs

This article is a correction to:

  1. Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate With Differences in the Expression of Selected Retinal miRNAs

    1. Read original article
Anca Hermenean, Anca Hermenean1,2*Maria Consiglia TrottaMaria Consiglia Trotta3Sami Gharbia,Sami Gharbia1,2Andrei Gelu HermeneanAndrei Gelu Hermenean4Victor Eduard PeteuVictor Eduard Peteu5Cornel BaltaCornel Balta1Coralia Cotoraci Coralia Cotoraci6*Carlo GesualdoCarlo Gesualdo7Settimio RossiSettimio Rossi7Mihaela Gherghiceanu,Mihaela Gherghiceanu4,5Michele D&#x;AmicoMichele D’Amico3
  • 1“Aurel Ardelean” Institute of Life Sciences, Vasile Goldis Western University of Arad, Arad, Romania
  • 2Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
  • 3Section of Pharmacology, Department of Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy
  • 4Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
  • 5Victor Babes National Institute of Pathology, Bucharest, Romania
  • 6Faculty of Medicine, Vasile Goldis Western University of Arad, Arad, Romania
  • 7Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy

A Corrigendum on
Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate with Differences in the Expression of Selected Retinal miRNAs

by Hermenean, A., Trotta, M. C., Gharbia, S., Hermenean, A. G., Peteu, V. E., Balta, C., Cotoraci, C., Gesualdo, C., Rossi, S., Gherghiceanu, M., D'Amico, M. Front. Pharmacol. 11:593514. doi: 10.3389/fphar.2020.593514

In the original article, there was a mistake in Figure 7 as published. The incorrect y-axis header was miR-27a-3p, miR-27b-3p, miR-20a-5p and miR-20b-5p in Figure 7A. The correct y-axis header in Figure 7A is miR-20a-3p, miR-106a-5p, miR-381-3p and miR-206-3p. Moreover, the incorrect miR-20b-5p graph in Figure 7B has been substituted with the correct miR-20b-5p graph. The corrected Figure 7 appears below.

FIGURE 7
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FIGURE 7. Age-related miRNA expression levels in aged retina. (A) Not dysregulated and (B) dysregulated retina miRNA expression levels. Data are reported as 2^−ΔCt and shown as mean ± SD of n = 10 observations for each experimental group; each run was performed in triplicate. Statistical significance was assessed by using one-way ANOVA, followed by Tukey’s multiple comparisons test. *p < 0.05 and **p < 0.01.

In the original article, there was a mistake in the legend for Figure 9 as published. The incorrect legend caption was “miR-27a-3p, miR-27b-3p, miR-20a-5p, and miR-20b-5p expression levels”. The correct legend caption is “miR-20a-3p, miR-106a-5p, miR-381-3p, and miR-206-3p expression levels”.

In the original article, there was a mistake in Figure 9 as published. The name of each graph was incorrectly reported as miR-27a-3p, miR-27b-3p, miR-20a-5p, and miR-20b-5p. The correct graph names are miR-20a-3p, miR-106a-5p, miR-381-3p, and miR-206-3p. The corrected Figure 9 appears below.

FIGURE 9
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FIGURE 9. Age-related miRNA expression levels not correlated with retina structure. No significant correlations were observed between RPE, INL, IPL, and GCL thickness and the miR-20a-3p, miR-106a-5p, miR-381-3p, and miR-206-3p expression levels. Pearson correlation analysis was used to evaluate the strength of association between pairs of variables, by including all the samples with different age and gender. Differences were considered statistically significant for p values < 0.05. RPE, retinal pigment cells; INL, retinal inner nuclear layer; IPL, retinal inner plexiform layer; GCL, retinal ganglion cell layer.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: aging, retina, gender, histology, electron microscopy, miRNAs

Citation: Hermenean A, Trotta MC, Gharbia S, Hermenean AG, Peteu VE, Balta C, Cotoraci C, Gesualdo C, Rossi S, Gherghiceanu M and D’Amico M (2021) Corrigendum: Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate with Differences in the Expression of Selected Retinal miRNAs. Front. Pharmacol. 12:652905. doi: 10.3389/fphar.2021.652905

Received: 13 January 2021; Accepted: 15 January 2021;
Published: 15 March 2021.

Edited and reviewed by:

Galina Sud’ina, Lomonosov Moscow State University, Russia

Copyright © 2021 Hermenean, Trotta, Gharbia, Hermenean, Peteu, Balta, Cotoraci, Gesualdo, Rossi, Gherghiceanu and D’Amico. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Anca Hermenean, YW5jYS5oZXJtZW5lYW5AZ21haWwuY29t; Coralia Cotoraci, Y2NvdG9yYWNpQHlhaG9vLmNvbQ==

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