Corrigendum: Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

A Corrigendum on
Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

Jiang Y-H, Jiang L-Y, Wang Y-C, Ma D-F and Li X (2020). Front. Pharmacol. 11:512. doi: 10.3389/fphar.2020.00512

In the original article, there was a mistake in Figure 3 as published. The wrong image of ROS generation in the 3 μm Que+ox-LDL group was unintentionally used in Figure 3C. The fully corrected Figure 3 appears below.

FIGURE 3

Figure 3 Effect of Quercetin on apoptosis, reactive oxygen species (ROS), and ΔΨm. Human aortic endothelial cells (HAECs) were cultured for 48 h in the presence of 50 μg/ml ox-LDL, or 50 μg/ml ox-LDL followed with different quercetin (3, 1 or 0.3 μmol/L), and untreated HAECs was used as normal control. (A) viability of HAECs was determined by MTT assay. (B) Apoptosis rate was determined by Annexin V-FITC/PI. (C) ROS generation was determined by 2',7'-dichlorofluorescin diacetate (DCFH-DA). (D) The degree of mitochondrial depolarization and ΔΨm was assayed by JC-1 staining and ΔΨm was assessed by the relative ratio of red fluorescence to green fluorescence via flow cytometer. ΔΨm reversibly changes color from green to red as the membrane potential increases (values of > 80–100 mV). *P < 0.05, vs untreated HAECs; ^ΔP < 0.05, vs ox-LDL; n = 3.

The authors apologize for this error that this does not change the scientific conclusions of the article in any way. The original article has been updated.