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Qi Wang1,2,3†
Cheng-Ting Zi1,2,3†
Jing Wang1,2,4Yu-Na Wang1,2,4Ye-Wei Huang1,2,4Xue-Qi Fu5*
Xuan-Jun Wang1,2,3,6*
Jun Sheng1,2,6*- 1Key Laboratory of Pu-erh Tea Science, Ministry of Education, Yunnan Agricultural University, Kunming, China
- 2Tea Research Center of Yunnan, Kunming, China
- 3College of Tea Science, Yunnan Agricultural University, Kunming, China
- 4College of Food Science and Technology, Yunnan Agricultural University, Kunming, China
- 5College of Life Sciences, Jilin University, Changchun, China
- 6State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Kunming, China
by Wang Q, Zi C-T, Wang J, Wang Y-N, Huang Y-W, Fu X-Q, Wang X-J and Sheng J (2018). Front. Pharmacol. 8:966. doi: 10.3389/fphar.2017.00966
In the original article, there was a mistake in Figure 4 as published. Panels 2 and 3 (cortical bone tissue stained with H&E for OVX Model and XLGB treated group, respectively) of Figure 4D in the original article was the same images as panels 2 and 3 of Figure 2E in Liang Q, Lv M, Zhang X, Hu J, Wu Y, Huang Y, Wang X and Sheng J (2018) Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro. Front. Physiol. 9:1225. doi: 10.3389/fphys.2018.01225. Based on the 3R (Reduction, Replacement, and Refinement) principle of experimental animals, the authors simultaneously and systematically evaluated the pharmacological effects of Dendrobium officinale Orchid extract, black tea extract, and thearubigins in preventing osteoporosis using the same batch of ovariectomized (OVX) female rats as the animal model of postmenopausal osteoporosis in the animal experiment study. They collected the data and published two articles and accidentally reused the same images in them. The corrected Figure 4 appears below.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
FIGURE 4
Figure 4 DOE treatment improves bone quality in OVX rats: (A) femoral BMD; (B) maximum deflection; (C) maximum load; (D) cortical bone tissue stained with H&E; (E) calculated cortical bone thickness; (F) trabecular bone tissue stained with H&E; and (G) calculated trabecular bone area. Representative images were acquired using a medical image analysis system at an original magnification of ×400. All data are presented as means ± SEM (n = 10). △P < 0.05, △△P < 0.01, and △△△P < 0.001 versus the sham group, and *P < 0.05, **P < 0.01, and ***P < 0.001 versus the OVX group.
Keywords: DOE, postmenopausal osteoporosis, ovariectomy, bone quality, osteoclastogenesis
Citation: Wang Q, Zi C-T, Wang J, Wang Y-N, Huang Y-W, Fu X-Q, Wang X-J and Sheng J (2020) Corrigendum: Dendrobium officinale Orchid Extract Prevents Ovariectomy-Induced Osteoporosis In Vivo and Inhibits RANKL-Induced Osteoclast Differentiation In Vitro. Front. Pharmacol. 11:578. doi: 10.3389/fphar.2020.00578
Received: 10 January 2020; Accepted: 15 April 2020;
Published: 30 April 2020.
Edited and reviewed by: George Qian Li, Western Sydney University, Australia
Copyright © 2020 Wang, Zi, Wang, Wang, Huang, Fu, Wang and Sheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xue-Qi Fu, ZnhxQGpsdS5lZHUuY24=; Xuan-Jun Wang, d2FuZ3h1YW5qdW5AZ21haWwuY29t; Jun Sheng, c2hlbmdqQHluYXUuZWR1LmNu
†These authors have contributed equally to this work