GENERAL COMMENTARY article

Front. Pharmacol., 24 September 2015

Sec. Experimental Pharmacology and Drug Discovery

Volume 6 - 2015 | https://doi.org/10.3389/fphar.2015.00214

Corrigendum: Impact of kinase activating and inactivating patient mutations on binary PKA interactions

  • Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck Innsbruck, Austria

Reason for Corrigendum:

There was a mistake in the figure legend for Figure 5 as published. The correct version of the figure legend (Figure 5B) appears below. The authors apologize for the mistake. This error does not change the scientific conclusions of the article in any way.

Figure 5. Impact of RIa mutations and cAMP elevation on PKA type I complexes. … (B) Following indicated modifications of RIa-F[1] sequences, combinations of wild type and mutant Rluc PCA tagged PKA subunits have been subjected to Rluc PCA measurements. The effect of isoproterenol (1 μM, 10 min; 48 h transient PCA reporter expression) on PKA complex formation has been determined (at least n = 3 independent experiments, ±SEM).

The original article was updated.

Statements

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Summary

Keywords

molecular interactions, patient mutations, cAMP-dependent protein kinase A, protein-fragment complementation assay, GPCR, Carney complex, Acrodysostosis

Citation

Röck R, Mayrhofer JE, Bachmann V and Stefan E (2015) Corrigendum: Impact of kinase activating and inactivating patient mutations on binary PKA interactions. Front. Pharmacol. 6:214. doi: 10.3389/fphar.2015.00214

Received

09 September 2015

Accepted

14 September 2015

Published

24 September 2015

Volume

6 - 2015

Edited and reviewed by

Apostolos Zarros, University of Glasgow, UK

Updates

Copyright

*Correspondence: Eduard Stefan,

This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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