This article is a correction to:
Ubiquitin C-Terminal Hydrolase L5 (UCHL5) Accelerates the Growth of Endometrial Cancer via Activating the Wnt/β-Catenin Signaling Pathway
Da Liu
Zixuan Song
Ling Ouyang- Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China
A Corrigendum on:
Ubiquitin C-terminal hydrolase L5 (UCHL5) accelerates the growth of endometrial cancer via activating the wnt/β-catenin signaling pathway
By Liu D, Song Z, Wang X and Ouyang L (2020). 10:865. doi: 10.3389/fonc.2020.00865
In the published article, there was an operator error in the western blot images of Figure 5. The original images provided by the authors were not spliced. The corrected Figure 5 and its caption “UCHL5 activated Wnt/β-catenin signaling and affected the expression of its target genes. (A) Relative protein levels of UCHL5 and β-catenin were detected by WB in HCE-1-A cells at 48 h after shRNA lentiviral infection (N = 3 times). *P < 0.05 vs. sh-NC. (B) Relative levels of cell cycle–related protein CyclinD1 and cell proliferation-related protein C-myc. (N = 3 times). *P < 0.05 vs. sh-NC. (C) Relative levels of cell apoptosis-related protein cleaved-caspase3 and anti-apoptosis protein Survivin (N = 3 times). *P < 0.05 vs. sh-NC. (D) Relative protein levels of UCHL5 and β-catenin were detected by WB in AN3-CA cells at 48 h after infected with overexpressed lentiviral vectors (N = 3 times). *P < 0.05 vs. empty vector. (E) Relative levels of CyclinD1 and C-myc (N = 3 times). *P < 0.05 vs. empty vector. (F) Relative levels of cleaved-caspase3 and Survivin (N = 3 times). *P < 0.05 vs. empty vector.” appear below.
FIGURE 5
Figure 5 UCHL5 activated Wnt/β-catenin signaling and affected the expression of its target genes. (A) Relative protein levels of UCHL5 and β-catenin were detected by WB in HCE-1-A cells at 48 h after shRNA lentiviral infection (N = 3 times). *P < 0.05 vs. sh-NC. (B) Relative levels of cell cycle–related protein CyclinD1 and cell proliferation-related protein C-myc. (N = 3 times). *P < 0.05 vs. sh-NC. (C) Relative levels of cell apoptosis-related protein cleaved-caspase3 and anti-apoptosis protein Survivin (N = 3 times). *P < 0.05 vs. sh-NC. (D) Relative protein levels of UCHL5 and β-catenin were detected by WB in AN3-CA cells at 48 h after infected with overexpressed lentiviral vectors (N = 3 times). *P < 0.05 vs. empty vector. (E) Relative levels of CyclinD1 and C-myc (N = 3 times). *P < 0.05 vs. empty vector. (F) Relative levels of cleavedcaspase3 and Survivin (N = 3 times). *P < 0.05 vs. empty vector.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: endometrial cancer, UCHL5, lentivirus vectors, Wnt/β-catenin pathway, XAV939
Citation: Liu D, Song Z, Wang X and Ouyang L (2022) Corrigendum: Ubiquitin C-Terminal hydrolase L5 (UCHL5) accelerates the growth of endometrial cancer via activating the Wnt/β-catenin signaling pathway. Front. Oncol. 12:992496. doi: 10.3389/fonc.2022.992496
Received: 12 July 2022; Accepted: 02 August 2022;
Published: 17 August 2022.
Edited and Reviewed by:
Alberto Farolfi, Scientific Institute of Romagna for the Study and Treatment of Tumors (IRCCS), ItalyCopyright © 2022 Liu, Song, Wang and Ouyang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Ling Ouyang, ouyl@sj-hospital.org