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Ding Zhang1
Hao Huang1Ting Zheng1
Lei Zhang1Binbin Cui2
Yanlong Liu2Shiheng Tan1Liyuan Zhao1
Tian Tian1
Lijing Gao1Qingzhen Fu1Zesong Cheng1
Yashuang Zhao1*- 1Department of Epidemiology, School of Public Health, NHC Key Laboratory of Etiology and Epidemiology (23618504), Harbin Medical University, Harbin, China
- 2Department of Colorectal Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China
A corrigendum on
Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression
By Zhang D, Huang H, Zheng T, Zhang L, Cui B, Liu Y, Tan S, Zhao L, Tian T, Gao L, Fu Q, Cheng Z and Zhao Y (2022) 12:924988. doi: 10.3389/fonc.2022.924988
Error in Figure/Table
In the published article, there was an error in Figure 4 as published. The microscopy slides of migration of “Vector” group and “PIGR+ LAMB3” group were misused in Figure 4G due to carelessness. The corrected Figure 4 and its caption appear below.
FIGURE 4
Figure 4 PIGR suppresses AKT-FOXO3/4 axis through LAMB3 (A) Relative LAMB3 mRNA expression of empty vector (Vector), PIGR-overexpressing (PIGR), LAMB3-overexpressing (LAMB3) and rescue experiment group (PIGR & LAMB3) in RKO and HCT-8 cells. Differences compared to Vector group (n = 3; one-way ANOVA, P adjusted by FDR). (B) Cell proliferation was detected by CCK-8 assay at 0, 24, 48, 72 and 96 hours in RKO and HCT-8 cells (n = 3; one-way ANOVA, P adjusted by FDR). (C) The colony formation assay of RKO and HCT-8 cells (n = 3; one-way ANOVA, P adjusted by FDR). (D–G) Wound healing, migration, and invasion assays were performed in RKO and HCT-8 cells (n = 3; one-way ANOVA, P adjusted by FDR). (H, I) Western blot showed altered protein levels of AKT-FOXO3/4 axis in empty vector, PIGR-overexpressing, LAMB3- overexpressing and rescue experiment group in RKO and HCT-8 cells. Differences compared to Vector group. Data are presented as the mean ± S.D. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: colorectal cancer, polymeric immunoglobulin receptor, prognostic marker, AKTFOXO3/4 axis, methylation-driven gene
Citation: Zhang D, Huang H, Zheng T, Zhang L, Cui B, Liu Y, Tan S, Zhao L, Tian T, Gao L, Fu Q, Cheng Z and Zhao Y (2022) Corrigendum: Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression. Front. Oncol. 12:1012871. doi: 10.3389/fonc.2022.1012871
Received: 06 August 2022; Accepted: 08 August 2022;
Published: 22 August 2022.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2022 Zhang, Huang, Zheng, Zhang, Cui, Liu, Tan, Zhao, Tian, Gao, Fu, Cheng and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Yashuang Zhao, emhhb195YXNodWFuZ0AyNjMubmV0