This article is a correction to:
Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma
Kainan Zhang1,2†
Hui Liu1†Mengsi Yu3Hui Zhao3Ning Yang1Xiaojuan Bi1Li Sun1Renyong Lin1*
Guodong Lü1,4*- 1State Key Laboratory of Pathogenesis, Prevention, and Treatment of Central Asian High Incidence Diseases, Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
- 2Graduate Academy, Xinjiang Medical University, Urumqi, China
- 3Department of Clinical Laboratory, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
- 4College of Pharmacy, Xinjiang Medical University, Urumqi, China
A Corrigendum on
Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma
By Zhang K, Liu H, Yu M, Zhao H, Yang N, Bi X, Sun L, Lin R and Lü G (2021). Front. Oncol. 11:650173. doi: 10.3389/fonc.2021.650173
In the original article, there was a mistake in Figure 6G as published. The label of Figure 6G should be HUH7 instead of HUH7-p65. The corrected Figure 6 appears below.
In the original article, there was a mistake in Figure 7 E, F as published. During the last round of revisions, we uploaded the wrong version of the file, resulting in a complete repetition of images E, F and C, D. “E, F” should have been the result of the HUH7 cell line. The corrected Figure 7 appears below.
FIGURE 6
Figure 6 LINC01667 has a regulatory relationship with MEG3 and NF-kB. (A) MEG3 expression levels in TCGA and GEPIA cohorts (normal = 160, tumor = 369, *P < 0.05). (B) Kaplan–Meier curves showing the DFS of patients with HCC according to high and low MEG3 expression in a TCGA cohort (n = 300). (C) Knockdown of LINC01667 increases the expression of MEG3. (D–G) LINC01667 could activate the NF-kB pathway. *P < 0.05. **P < 0.01, ***P < 0.001. oeNC represents the empty vector group, and oeLINC01667 represents the overexpression LINC01667 group, ssiNC represents the random sequence, and ssiLINC01667 represents the knockdown LINC01667 group.
FIGURE 7
Figure 7 LINC01667 modulates Sorafenib and Regorafenib response in HCC cells. Effect of Regorafenib treatment in cells with (A, C) knockdown of LINC01667 (HepG2 and SMMC-7721) or (E) stable overexpression of LINC01667 (HUH7) compared with the transfected controls. Effect of Sorafenib treatment in cells with (B, D) knockdown of LINC01667 (HepG2 and SMMC-7721) or (F) stable overexpression of LINC01667 (HUH7) compared with the transfected controls. All experiments were performed in 5 copies. *P < 0.05, ***P < 0.001. oeNC represents the empty vector group, and oeLINC01667 represents the overexpression LINC01667 group, ssiNC represents the random sequence group, and ssiLINC01667 represents the knockdown LINC01667 group.
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: hepatocellular carcinoma, LINC01667, diagnostic biomarker, overall survival, carcinogenesis
Citation: Zhang K, Liu H, Yu M, Zhao H, Yang N, Bi X, Sun L, Lin R and Lü G (2021) Corrigendum: Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma. Front. Oncol. 11:785394. doi: 10.3389/fonc.2021.785394
Received: 29 September 2021; Accepted: 30 September 2021;
Published: 15 October 2021.
Edited and reviewed by:
Fei-Ting Hsu, China Medical University, TaiwanCopyright © 2021 Zhang, Liu, Yu, Zhao, Yang, Bi, Sun, Lin and Lü. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Guodong Lü, bGdkX3hqQHFxLmNvbQ==; Renyong Lin, cmVueW9uZ2xpbkB4am11LmVkdS5jbg==
†These authors have contributed equally to this work and share first authorship