TRPC1 Inhibits Cell Proliferation/Invasion and Is Predictive of a Better Prognosis of Esophageal Squamous Cell Carcinoma
- 1Department of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, China
- 2Department of Breast-Thyroid-Surgery and Cancer Research Center, Xiang’an Hospital of Xiamen University, Xiamen, China
- 3Oncological Research Laboratory, Cancer Hospital of Shantou University Medical College, Shantou, China
- 4Clinical Laboratory, Cancer Hospital of Shantou University Medical College, Shantou, China
- 5Guangdong Provincial Key Laboratory for Breast Cancer Diagnosis and Treatment, Cancer Hospital of Shantou University Medical College, Shantou, China
A Corrigendum on
TRPC1 Inhibits Cell Proliferation/Invasion and Is Predictive of a Better Prognosis of Esophageal Squamous Cell Carcinoma
By Zeng Y-Z, Zhang Y-Q, Chen J-Y, Zhang L-Y, Gao W-L, Lin X-Q, Huang S-M, Zhang F and Wei X-L (2021). Front. Oncol. 11:627713. doi: 10.3389/fonc.2021.627713
In the original article, there was a mistake in Figure 3D as published. The picture of Figure 3D was misused and needs to be corrected. The corrected Figure 3D appears below.
Figure 3 Knockdown of TRPC1 by transfection with siRNA promoted the proliferation, wound healing, migration, and invasion abilities of EC9706 cells. (A) Western blotting showed TRPC1 expression in four esophageal squamous carcinoma cell lines: Eca109, EC9706, KYSE510, and KYSE150. (B) Representative western blot showing the effect of siRNA directed against TRPC1 on the level of TRPC1 protein in EC9706. (C) Analysis of proliferation of cells transfected with siTRPC1 by CCK-8 assay. Cell proliferation was measured 24, 48, 72, and 96h post-transfection. After treatment with siTRPC1, the viability of EC9706 cells was significantly increased. (D) Cellular wound healing after knockdown of TRPC1 in EC9706 cells (magnification: 100×). The rate of wound healing of EC9706-siTRPC1-1 or EC9706-siTRPC1-2 cells was significantly higher than that of EC9706-siNC cells (P<0.01). (E) Cell migration and invasion after knockdown of TRPC1 (magnification: 100×). The cells of the silenced expression group (EC9706-siTRPC1-1 or EC9706-siTRPC1-2) had higher migration and invasion abilities than those of the control group (EC9706-siNC), (P<0.05). NC represented as negative control. *P < 0.05, **P < 0.01, ****P < 0.0001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: TRPC1, esophageal squamous cell carcinoma, prognosis, cell proliferation, migration and invasion
Citation: Zeng Y-Z, Zhang Y-Q, Chen J-Y, Zhang L-Y, Gao W-L, Lin X-Q, Huang S-M, Zhang F and Wei X-L (2021) Corrigendum: TRPC1 Inhibits Cell Proliferation/Invasion and Is Predictive of a Better Prognosis of Esophageal Squamous Cell Carcinoma. Front. Oncol. 11:767805. doi: 10.3389/fonc.2021.767805
Received: 31 August 2021; Accepted: 16 September 2021;
Published: 06 October 2021.
Edited and reviewed by:
Luisa Accardi, National Institute of Health (ISS), ItalyCopyright © 2021 Zeng, Zhang, Chen, Zhang, Gao, Lin, Huang, Zhang and Wei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xiao-Long Wei, weixiaolonghh@126.com
†These authors have contributed equally to this work