Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory
- 1Division of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
- 2Surrey Sleep Research Centre, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
A Corrigendum on
Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory
by Maywood, E. S., Chesham, J. E., Winsky-Sommerer, R., Smyllie, N. J., and Hastings, M. H. (2021). Front. Neurosci. 15:639281. doi: 10.3389/fnins.2021.639281
In the original article, there was an error in assignment of mouse strain identity.
A correction has been made to **Materials and Methods**, **Animals and housing**, **Paragraph number 1**:
All experiments were conducted in accordance with the UK Animals (Scientific Procedures) Act of 1986, with local ethical approval (MRC LMB, AWERB). Drd1a-Cre mice (Tg(Drd1-cre)EY266Gsat/Mmucd, RRID:MMRRC_030779-UCD) were purchased from the GENSAT project (Rockefeller University, New York, United States), through the Mutant Mouse Regional Resource Centers (MMRRC, United States). ROSA-YFP mice were provided by Dr. A. McKenzie (MRC LMB). Temporally chimeric mice were created by crossing Drd1a-Cre, ROSA26-EYFP mice with homozygotes for the floxed CK1ε Tau allele (Smyllie et al., 2016). All mice expressed the PER2::LUC bioluminescent reporter (Yoo et al., 2005) and had a C57/BL/6J background. This generated four genotypes: CRE-negative, CK1εWT/WT; CRE-positive, CK1εWT/WT; CRE-negative, CK1εTau/Tau (Tau controls); CRE-positive, CK1εTau/Tau (chimera). The first two groups were combined as WT, in light of no differences between them. Males aged 4–6 months old were used to avoid the estrous modulation of activity patterns.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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References
Smyllie, N. J., Chesham, J. E., Hamnett, R., Maywood, E. S., and Hastings, M. H. (2016). Temporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleus. Proc. Natl. Acad. Sci. U. S. A. 113, 3657–3662. doi: 10.1073/pnas.1511351113
Keywords: REM sleep, NREM sleep, electroencephalogram, circadian misalignment, suprachiasmatic nucleus
Citation: Maywood ES, Chesham JE, Winsky-Sommerer R, Smyllie NJ and Hastings MH (2021) Corrigendum: Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory. Front. Neurosci. 15:740799. doi: 10.3389/fnins.2021.740799
Received: 13 July 2021; Accepted: 16 July 2021;
Published: 05 August 2021.
Edited and reviewed by: Natsuko Tsujino, University of Tsukuba, Japan
Copyright © 2021 Maywood, Chesham, Winsky-Sommerer, Smyllie and Hastings. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Elizabeth Susan Maywood, emaywood@mrc-lmb.cam.ac.uk; Michael Harvey Hastings, mha@mrc-lmb.cam.ac.uk